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Letter to Shareholders
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| Letter to Shareholders | |
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Notice of 2024 Annual General Meeting of
Shareholders |
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Time and Date
June 5, 2024
at 8:30 a.m. local time at the offices of Mourant Governance Services (Cayman) Limited, at 94 Solaris Avenue, Camana Bay, Grand Cayman KY1-1108, Cayman Islands |
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Record Date
The record date for the determination
of the shareholders entitled to vote at our Annual Meeting of Shareholders, or any adjournments or postponements thereof, is 5:00 a.m. Cayman Islands Time on April 19, 2024 |
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Nasdaq:
BGNE |
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HKEX:
06160 |
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SSE:
688235 |
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| Notice of 2024 Annual General Meeting of Shareholders | |
| Notice of 2024 Annual General Meeting of Shareholders | |
| Notice of 2024 Annual General Meeting of Shareholders | |
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Your vote is important.
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| Notice of 2024 Annual General Meeting of Shareholders | |
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Table of Content
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| | | | | 1 | | | |
| | | | | 7 | | | |
| | | | | 9 | | | |
| | | | | 25 | | | |
| | | | | 27 | | | |
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| | | | | 32 | | | |
| | | | | 35 | | | |
| | | | | 37 | | | |
| | | | | 98 | | | |
| Proposal 16 Non-binding, Advisory Vote on Frequency of Future Advisory Votes on Executive Compensation | | | | | 99 | | |
| Proposals 17(a) and 17(b) Approval of Third Amended and Restated 2016 Share Option and Incentive Plan and Consultant Sublimit | | | | | 100 | | |
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Proposal 18 Approval of Fourth Amended and Restated 2018 Employee
Share Purchase Plan |
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| | | | | 115 | | | |
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| | | | | 171 | | | |
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| | | | | 180 | | | |
| Appendix A Third Amended and Restated 2016 Share Option and Incentive Plan | | | | | A-1 | | |
| Appendix B Fourth Amended and Restated 2018 Employee Share Purchase Plan | | | | | B-1 | | |
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General Information
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| General Information | |
| General Information | |
| General Information | |
| General Information | |
| General Information | |
| General Information | |
| General Information | |
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Proposals 1 — 4. Election of Directors
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| Proposals 1 — 4. Election of Directors | |
| Proposals 1 — 4. Election of Directors | |
Name
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Position(s)
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Director Since
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Age
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Dr. Olivier Brandicourt | | | | | Director | | | | | | 2024 | | | | | | 68 | | |
Donald W. Glazer | | | | | Director | | | | | | 2013 | | | | | | 79 | | |
Michael Goller | | | | | Director | | | | | | 2015 | | | | | | 49 | | |
Dr. Corazon (Corsee) D. Sanders | | | | | Director | | | | | | 2020 | | | | | | 67 | | |
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Dr. Olivier Brandicourt
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 68
Director Since: Jan. 2024 Committees: Audit Committee
Commercial and Medical Affairs Advisory Committee |
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Experience:
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2019-Present:
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Blackstone Life Sciences (Senior Advisor)
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2015-2019:
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Sanofi S.A. (Chief Executive Officer)
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Prior:
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Bayer HealthCare AG (Chief Executive Officer) Pfizer Inc. (Executive Leadership Team Member and President and General Manager of the Emerging Markets and Established Products business unit) |
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Other Public Company Directorships:
2020-Present: Alnylam Pharmaceuticals, Inc. 2022-Present: BenevolentAI S.A. Former Public Company Directorships:
Sanofi S.A.
Qualifications:
Dr. Brandicourt studied medicine in Paris, specializing in Infectious Diseases and Tropical Medicine at the University of Paris V. He holds an advanced degree in Cellular and Immunological Pathophysiology from Paris Descartes University and a Master’s Degree in Biology from the University of Paris XII. We believe that Dr. Brandicourt’s extensive global operational, commercial and senior management experience in the healthcare sector qualifies him to serve as a member of the Board of Directors.
As of April 1, 2024, Dr. Brandicourt was interested in 27,794 ordinary shares of the Company within the meaning of Part XV of the Hong Kong Securities and Futures Ordinance (the “SFO”). The beneficial ownership rules of the SEC differ from those of the SFO and the HK Listing Rules.
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| Proposals 1 — 4. Election of Directors | |
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Donald W. Glazer
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 79
Director Since: Feb. 2013 Committees: Nominating and Corporate Governance Committee (Chair)
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Experience:
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2005-Present
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GMO Trust (Chair of the Board of Trustees)
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2000-Present:
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GMO Trust (Member of the Board of Trustees)
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1997-Present:
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Goodwin Procter LLP (Advisory Counsel)
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Prior:
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Provant, Inc. (Co-Founder, Secretary and Vice Chair) Mugar/Glazer Holdings (President) New England Television Corp. and WHDH-TV, Inc. (Vice Chairman of Finance) Ropes & Gray LLP, Emerging Companies Group (Partner and Chair, Emerging Companies Group) Harvard Law School (Lecturer) |
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Other Public Company Directorships:
N/A Former Public Company Directorships:
N/A
Qualifications:
Mr. Glazer received his A.B. from Dartmouth College in June 1966; J.D. from Harvard Law School in June 1969, where he was an editor of the Harvard Law Review; and L.L.M. from the University of Pennsylvania Law School in May 1970. Additionally, Mr. Glazer is a co-author of both Glazer and FitzGibbon on Legal Opinions, Third Edition (Aspen Publishers) and Massachusetts Corporation Law & Practice, Second Edition (Aspen Publishers).
We believe that Mr. Glazer’s qualifications to serve on the Board of Directors include his extensive leadership, executive, managerial, business, and corporate legal experience.
As of April 1, 2024, Mr. Glazer was interested in 3,108,659 ordinary shares of the Company within the meaning of Part XV of the SFO. The beneficial ownership rules of the SEC differ from those of the SFO and the HK Listing Rules.
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| Proposals 1 — 4. Election of Directors | |
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Michael Goller
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 49
Director Since: Apr. 2015 Committees: Nominating and Corporate Governance Committee
Scientific Advisory Committee |
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Experience:
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2005-Present:
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Baker Brothers Investments (Partner)
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Prior:
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JPMorgan Partners, LLC (Associate)
Merrill Lynch and Co. (Investment Banker) |
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Other Public Company Directorships:
2015-Present: DBV Technologies SA Former Public Company Directorships:
N/A
Qualifications:
Mr. Goller received a B.S. in Molecular and Cell Biology from The Pennsylvania State University in May 1997, and Master’s Degrees in both Biotechnology (School of Engineered and Applied Sciences) and Business Administration (Wharton School) from the University of Pennsylvania in May 2005. We believe that Mr. Goller is qualified to serve on the Board of Directors based on his experience in the life sciences industry and for his knowledge in financial and corporate development matters.
As of April 1, 2024, Mr. Goller was interested in 453,232 ordinary shares of the Company within the meaning of Part XV of the SFO. The beneficial ownership rules of the SEC differ from those of the SFO and the HK Listing Rules.
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| Proposals 1 — 4. Election of Directors | |
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Dr. Corazon (Corsee) D. Sanders
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 67
Director Since: Aug. 2020 Committees: Audit Committee Commercial and Medical Affairs Advisory Committee Scientific Advisory Committee
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Experience:
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2019-2020:
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Bristol Myers Squibb Corporation (Transition Advisor)
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2018-2019:
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| | Celgene Corporation (Strategic Advisor to the Chief Medical Officer) | | | |||||
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Prior:
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Juno Therapeutics Inc. (Member of the Executive Committee and Executive Vice President of Development Operations) Genentech/Roche (Global Head Clinical Operations; Global Head of Biometrics Group; and Co-Chair of the Portfolio Management Committee) |
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Other Public Company Directorships:
2019-Present: Molecular Templates Inc. 2020-Present: Legend Biotech Corporation 2021-Present: Ultragenyx Pharmaceutical Inc. Former Public Company Directorships:
N/A
Qualifications:
Dr. Sanders earned her B.S. and M.S. in statistics, graduating magna cum laude from the University of the Philippines, and her M.A. and Ph.D. in statistics from the Wharton Doctoral Program at the University of Pennsylvania. We believe that Dr. Sanders’ extensive experience and knowledge in the healthcare sector and her scientific and leadership experience qualify her to serve on, and contribute to the diversity of, the Board of Directors.
As of April 1, 2024, Dr. Sanders was interested in 136,500 ordinary shares of the Company within the meaning of Part XV of the SFO. The beneficial ownership rules of the SEC differ from those of the SFO and the HK Listing Rules.
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| Proposals 1 — 4. Election of Directors | |
| Proposals 1 — 4. Election of Directors | |
Name
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Position(s)
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Director Since
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Age
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Dr. Margaret Dugan | | | | | Director | | | | | | 2022 | | | | | | 67 | | |
Anthony C. Hooper | | | | | Director | | | | | | 2020 | | | | | | 69 | | |
Ranjeev Krishana | | | | | Director | | | | | | 2014 | | | | | | 50 | | |
John V. Oyler | | | | | Director | | | | | | 2010 | | | | | | 56 | | |
Dr. Alessandro Riva | | | | | Director | | | | | | 2022 | | | | | | 63 | | |
Dr. Xiaodong Wang | | | | | Director | | | | | | 2016 | | | | | | 60 | | |
Qingqing Yi | | | | | Director | | | | | | 2014 | | | | | | 52 | | |
| Proposals 1 — 4. Election of Directors | |
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Anthony C. Hooper
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 69
Director Since: Jan. 2020 Committees: Audit Committee (Chair)
Commercial and Medical Affairs Advisory Committee (Chair)
Nominating and Corporate Governance Committee
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Experience:
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2020-Present:
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Amgen Inc. (Consultant)
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2011-2020:
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| | Amgen Inc. (Executive Vice President and Executive Vice President, Global Commercial Operations) | | | |||||
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Prior:
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Bristol Myers Squibb Company (Senior Vice President, Commercial Operations and President, U.S., Japan and Intercontinental; President, Americas; and President, U.S. Pharmaceuticals, Worldwide Pharmaceuticals Group) Wyeth Laboratories (Assistant Vice President of Global Marketing) |
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Other Public Company Directorships:
2020-Present: MannKind Corporation Former Public Company Directorships:
N/A
Qualifications:
Mr. Hooper earned his law and MBA degrees from the University of South Africa in 1978 and 1988, respectively. We believe Mr. Hooper’s extensive experience and knowledge in the healthcare sector and broad international experience in pharmaceutical commercial operations qualify him to serve on the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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Ranjeev Krishana
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| | MEMBER and LEAD DIRECTOR OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 50
Director Since: Oct. 2014 Committees: Commercial and Medical Affairs Advisory Committee Compensation Committee
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Experience:
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2011-Present:
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Baker Bros. Advisors LP (Partner)
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Prior:
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Pfizer, Inc. (various commercial, strategy and business development leadership roles) Pfizer China (Senior Director and Member of China Leadership Team) Accenture plc (Strategy Consultant) |
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Other Public Company Directorships:
N/A Former Public Company Directorships:
N/A
Qualifications:
Mr. Krishana received an A.B. in Economics and Political Science from Brown University in May 1995, and a Master of Public Policy from Harvard University in June 2011. We believe Mr. Krishana’s knowledge of the healthcare sector across international markets qualifies him to serve on the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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Dr. Xiaodong Wang
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 60
Director Since: Feb. 2016 Committees: Scientific Advisory Committee (Co-Chair)
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Experience:
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2020-Present:
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Tsinghua University (Chair Professor)
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2013-Present:
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Chinese Academy of Sciences (Foreign Associate)
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2010-Present:
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BeiGene, Ltd. (Co-Founder)
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2004-Present:
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National Academy of Science, USA (Member)
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2003-Present:
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| | National Institute of Biological Sciences in Beijing (Founding Co-Director; Director and Investigator) | | | |||||
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Prior:
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Joyant Pharmaceuticals, Inc. (Founder) University of Texas Southwestern Medical Center (George L. MacGregor Distinguished Chair Professor in Biomedical Sciences) Howard Hughes Medical Institute (Investigator) |
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Other Public Company Directorships:
2021-Present: Clover Biopharmaceutical Ltd. (Non-Executive Director and Member of the Compensation Committee) Former Public Company Directorships:
N/A
Qualifications:
Dr. Wang received his B.S. in Biology from Beijing Normal University in July 1984 and his Ph.D. in Biochemistry from the University of Texas Southwestern Medical Center in May 1991. We believe that Dr. Wang’s extensive experience in cancer drug research, combined with his experience in the biotech industry, qualifies him to serve as a member of the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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Dr. Margaret Dugan
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 67
Director Since: Feb. 2022 Committees: Commercial and Medical Affairs Advisory Committee Compensation Committee (Chair) Scientific Advisory Committee
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Experience:
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2023-Present:
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Schrodinger, Inc. (Chief Medical Officer)
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2023-Present:
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Dracen Pharmaceuticals (Medical Consultant)
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2021-Present:
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| | SonALAsense Pharmaceuticals (Scientific Advisory Board Member) | | | |||||
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2021-2022
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SonALAsense Pharmaceuticals (Senior Medical Consultant)
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2018-Present:
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| | Salarius Pharmaceuticals (Senior Medical Advisor and Consultant) | | | |||||
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Prior:
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Novartis Pharmaceuticals Corp. (Senior Vice President of Clinical Development) Dracen Pharmaceuticals (Chief Medical Officer) Schering-Plough (Director, Oncology Clinical Research) American Cyanamid (Deputy Director, Clinical Research, Oncology) New York University Medical Center (Research Fellow, Hematology and Oncology Clinical Trials) |
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Other Public Company Directorships:
N/A Former Public Company Directorships:
N/A
Qualifications:
Dr. Dugan received her B.A. from New York University in 1977 and her M.D. in hematology and oncology from New York University in 1981. We believe that Dr. Dugan’s extensive scientific and leadership experience in the healthcare sector qualifies her to serve on, and contribute to the diversity of, the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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John V. Oyler
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| | CHAIRMAN OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 55
Director Since: Oct. 2010 Committees: N/A
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Experience:
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2010-Present:
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| | BeiGene, Ltd. (Co-Founder, Chairman and Chief Executive Officer) | | | |||||
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Prior:
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BioDuro, LLC (President and Chief Executive Officer)
Galenea Corp. (Chief Executive Officer) Telephia, Inc. (Founder and President) Genta, Inc. (Co-Chief Executive Officer) McKinsey & Company (Management Consultant) |
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Other Public Company Directorships:
N/A Former Public Company Directorships:
N/A
Qualifications:
Mr. Oyler received his B.S. from the Massachusetts Institute of Technology in June 1990 and an MBA from Stanford University in January 1996. We believe that Mr. Oyler’s extensive leadership, executive, managerial, business and pharmaceutical and biotechnology company experience, along with his years of industry experience in the development of pharmaceutical products, qualifies him to serve as a member of the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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Dr. Alessandro Riva
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 63
Director Since: Feb. 2022 Committees: Nominating and Corporate Governance Committee
Scientific Advisory Committee (Co-Chair)
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Experience:
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2023-Present:
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| | Transgene S.A. (Chairman and Chief Executive Officer) | | | |||||
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2021-2023:
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Intima Bioscience (Chief Executive Officer)
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2019-2021:
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Ichnos Sciences (Chief Executive Officer)
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2017-2019:
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| | Gilead Sciences (Executive Vice President and Global Head of Oncology Therapeutics and Cell & Gene Therapy) | | | |||||
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Prior:
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| | Novartis Pharmaceuticals (Executive Vice President and Global Head of Oncology Development and Medical Affairs) Novartis Oncology (Interim President) Breast Cancer International Research Group (Co-Founder) Cancer International Research Group (Co-Founder and Chief Executive Officer) Farmitalia Carlo Erba Rhône-Poulenc Rorer Aventis |
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Other Public Company Directorships:
2022-Present: Transgene SA (Chair) 2021-Present: Century Therapeutics Former Public Company Directorships:
N/A
Qualifications:
Dr. Riva received his M.D. in medicine and surgery from the University of Milan and board certification in oncology and hematology from the same institution. We believe that Dr. Riva’s extensive scientific and management experience in the healthcare sector qualifies him to serve on the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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Qingqing Yi
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| | MEMBER OF THE BOARD OF DIRECTORS, BEIGENE, LTD. | | | |||||||
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Age: 52
Director Since: Oct. 2014 Committees: Compensation Committee
Scientific Advisory Committee
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Experience:
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2005-Present:
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Hillhouse Capital (Partner)
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Prior:
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| | China International Capital Corporation (Equity Research Analyst) | | | |||||
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Other Public Company Directorship:
2020-Present: JD Health International Inc. Former Public Company Directorships:
N/A
Qualifications:
Mr. Yi received a B.S. degree in Engineering from Shanghai Maritime University in July 1995 and an MBA from the University of Southern California in May 2003. We believe Mr. Yi’s extensive experience in capital markets and knowledge of the healthcare sector qualify him to serve on the Board of Directors. |
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| Proposals 1 — 4. Election of Directors | |
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The Board of Directors recommends that shareholders vote FOR the election of each of the Class II director nominees listed above.
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Proposal 5. Ratification of Appointment of
Independent Auditors |
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2023 (US$)
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2022 (US$)
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Fee Category
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Ernst & Young LLP
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Ernst & Young
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Ernst & Young
Hua Ming LLP |
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Total
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Ernst & Young LLP
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Ernst & Young
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Ernst & Young
Hua Ming LLP |
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Total
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| ||||||||||||||||||||||||
Audit Fees | | | | | 4,436,032(1) | | | | | | 843,443 | | | | | | 1,777,497 | | | | | | 7,056,972 | | | | | | 3,250,000 | | | | | | 749,194 | | | | | | 3,038,019 | | | | | | 7,037,213 | | |
Tax Fees | | | | | 63,968 | | | | | | — | | | | | | — | | | | | | 63,968 | | | | | | 63,978 | | | | | | 40,023 | | | | | | — | | | | | | 40,023 | | |
All Other Fees | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 16,834 | | | | | | — | | | | | | 16,834 | | |
Total Fees | | | | | 4,500,000 | | | | | | 843,443 | | | | | | 1,777,497 | | | | | | 7,120,940 | | | | | | 3,250,000 | | | | | | 806,051 | | | | | | 3,038,019 | | | | | | 7,094,070 | | |
| Proposal 5. Ratification of Appointment of Independent Auditors | |
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The Board of Directors recommends that shareholders vote FOR ratification of the appointment of Ernst & Young LLP, Ernst & Young and Ernst & Young Hua Ming LLP as our independent auditors for the fiscal year ending December 31, 2024.
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Proposal 6. Approval of Board Authority to Fix
Auditor Compensation |
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The Board of Directors recommends that shareholders vote FOR authorization to the Board of Directors to fix auditor compensation for the fiscal year ending December 31, 2024.
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Proposal 7. General Mandate to Issue Shares
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The Board of Directors recommends that shareholders vote FOR the approval of the General Mandate to Issue Shares.
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Proposal 8. General Mandate to Repurchase Shares
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The Board of Directors recommends that shareholders vote FOR the
approval of the General Mandate to Repurchase Shares. |
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Explanatory Statement
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|
| Explanatory Statement | |
| | |
Highest
(HK$) |
| |
Lowest
(HK$) |
| ||||||
Apr-23 | | | | | 167.300 | | | | | | 124.900 | | |
May-23 | | | | | 161.800 | | | | | | 131.000 | | |
Jun-23 | | | | | 137.400 | | | | | | 106.200 | | |
Jul-23 | | | | | 139.900 | | | | | | 105.700 | | |
Aug-23 | | | | | 132.700 | | | | | | 112.500 | | |
Sep-23 | | | | | 129.600 | | | | | | 107.500 | | |
Oct-23 | | | | | 118.600 | | | | | | 93.200 | | |
Nov-23 | | | | | 126.100 | | | | | | 108.100 | | |
Dec-23 | | | | | 113.700 | | | | | | 101.300 | | |
Jan-24 | | | | | 110.900 | | | | | | 87.900 | | |
Feb-24 | | | | | 108.900 | | | | | | 82.650 | | |
Mar-24 | | | | | 112.100 | | | | | | 91.150 | | |
Apr-24 up to the Latest Practicable Date | | | | | 95.150 | | | | | | 91.700 | | |
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Proposal 9. Connected Person Placing
Authorization I |
|
| Proposal 9. Connected Person Placing Authorization I | |
Name of Shareholder
|
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Capacity / Nature of Interest
|
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Number of
Shares/ Underlying Shares |
| |
Approximate
Percentage of Holding(1) |
| ||||||
Julian C. Baker(2) | | | Beneficial owner/Interest in controlled corporations/Person having a security interest in shares | | | | | 138,757,831 | | | | | | 10.21% | | |
Felix J. Baker(2) | | | Beneficial owner/Interest in controlled corporations/Person having a security interest in shares | | | | | 138,757,831 | | | | | | 10.21% | | |
Baker Bros. Advisors (GP) LLC(2) | | | Investment manager/Other | | | | | 138,302,171 | | | | | | 10.17% | | |
Baker Bros. Advisors LP(2) | | | Investment manager/Other | | | | | 138,302,171 | | | | | | 10.17% | | |
Baker Brothers Life Sciences Capital, L.P.(2) | | | Interest in controlled corporations/Other | | | | | 126,893,311 | | | | | | 9.33% | | |
HHLR Advisors, Ltd.(3) | | | Investment manager | | | | | 133,587,655 | | | | | | 9.83% | | |
HHLR Fund, L.P.(3) | | | Beneficial owner | | | | | 129,433,059 | | | | | | 9.52% | | |
| Proposal 9. Connected Person Placing Authorization I | |
|
The Board of Directors recommends that shareholders vote FOR the
approval of the Connected Person Placing Authorization I. |
|
|
Proposal 10. Connected Person Placing
Authorization II |
|
| Proposal 10. Connected Person Placing Authorization II | |
Name of Shareholder
|
| |
Capacity / Nature of Interest
|
| |
Number of
Shares/ Underlying Shares |
| |
Approximate
Percentage of Holding(1) |
| ||||||
Amgen Inc. | | | Beneficial owner | | | | | 246,269,426 | | | | | | 18.11% | | |
|
The Board of Directors recommends that shareholders vote FOR the
approval of the Connected Person Placing Authorization II. |
|
|
Proposals 11 – 14. Proposed Grants of Restricted
Share Units and Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| | |
Latest Practicable Date(1)
|
| |
Assuming full vesting or
target vesting of the Proposed Equity Grants(2) |
| ||||||||||||||||||
| | |
No. of shares
|
| |
%(3)
|
| |
No. of shares
|
| |
%
|
| ||||||||||||
Mr. Oyler
|
| | | | 74,879,026(4) | | | | | | 5.51% | | | | | | 75,858,732 | | | | | | 5.57% | | |
Dr. Wang
|
| | | | 20,313,993(5) | | | | | | 1.49% | | | | | | 20,422,842 | | | | | | 1.50% | | |
Dr. Brandicourt
|
| | | | 27,794(6) | | | | | | 0.002% | | | | | | 44,122 | | | | | | 0.003% | | |
Dr. Dugan
|
| | | | 113,815(7) | | | | | | 0.008% | | | | | | 130,143 | | | | | | 0.01% | | |
Mr. Glazer
|
| | | | 3,108,659(8) | | | | | | 0.23% | | | | | | 3,124,987 | | | | | | 0.23% | | |
Mr. Goller
|
| | | | 453,232(9) | | | | | | 0.03% | | | | | | 469,560 | | | | | | 0.03% | | |
Mr. Hooper
|
| | | | 183,885(10) | | | | | | 0.01% | | | | | | 200,213 | | | | | | 0.01% | | |
Mr. Krishana
|
| | | | 453,232(11) | | | | | | 0.03% | | | | | | 469,560 | | | | | | 0.03% | | |
Dr. Riva
|
| | | | 113,815(12) | | | | | | 0.008% | | | | | | 130,143 | | | | | | 0.01% | | |
Dr. Sanders
|
| | | | 136,500(13) | | | | | | 0.01% | | | | | | 152,828 | | | | | | 0.01% | | |
Mr. Yi
|
| | | | 436,150(14) | | | | | | 0.03% | | | | | | 452,478 | | | | | | 0.03% | | |
Other Shareholders
|
| | | | 1,259,304,268 | | | | | | 92.63% | | | | | | 1,259,304,268 | | | | | | 92.54% | | |
Total
|
| | | | 1,359,524,369 | | | | | | 100% | | | | | | 1,360,759,876 | | | | | | 100% | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | | Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | | Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
|
| Dr. Alessandro Riva | | |
Dr. Corazon (Corsee) D. Sanders
|
| |
Mr. Qingqing Yi
|
|
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
| |
Mr. Michael Goller
|
|
| Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | |
Mr. Donald W. Glazer
|
| |
Mr. Michael Goller
|
|
| Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | |
Dr. Margaret Dugan
|
| |
Mr. Michael Goller
|
|
| Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | |
Dr. Margaret Dugan
|
| |
Mr. Donald W. Glazer
|
|
| Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | |
Dr. Margaret Dugan
|
| |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | |
Mr. Ranjeev Krishana
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | | Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | |
Mr. Anthony C. Hooper
|
| |
Dr. Alessandro Riva
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | | Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | |
Mr. Anthony C. Hooper
|
| |
Mr. Ranjeev Krishana
|
|
|
Dr. Corazon (Corsee) D. Sanders
|
| | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | | Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | |
Mr. Anthony C. Hooper
|
| |
Mr. Ranjeev Krishana
|
|
| Dr. Alessandro Riva | | | Mr. Qingqing Yi | | | | |
|
Proposals 11 – 14. Proposed Grants of Restricted Share Units and
Performance Share Units |
|
| Dr. Olivier Brandicourt | | | Dr. Margaret Dugan | | |
Mr. Donald W. Glazer
|
|
| Mr. Michael Goller | | | Mr. Anthony C. Hooper | | |
Mr. Ranjeev Krishana
|
|
| Dr. Alessandro Riva | | |
Dr. Corazon (Corsee) D. Sanders
|
| | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
For the year ended December 31,
|
| |||||||||||||||
| | |
2021
(US$’000) |
| |
2022
(US$’000) |
| |
2023
(US$’000) |
| |||||||||
| | |
(audited)
|
| |
(audited)
|
| |
(audited)
|
| |||||||||
Revenue | | | | | | | | | | | | | | | | | | | |
— Product revenue, net
|
| | | | 633,987 | | | | | | 1,254,612 | | | | | | 2,189,852 | | |
— Collaboration revenue
|
| | | | 542,296 | | | | | | 161,309 | | | | | | 268,927 | | |
| | | | | 1,176,283 | | | | | | 1,415,921 | | | | | | 2,458,779 | | |
Research and development (“R&D”) costs | | | | | (1,459,239) | | | | | | (1,640,508) | | | | | | (1,778,594) | | |
Net loss attributable to the Company | | | | | (1,457,816) | | | | | | (2,003,815) | | | | | | (881,708) | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
As of December 31,
|
| |||||||||||||||
| | |
2021
(US$’000) |
| |
2022
(US$’000) |
| |
2023
(US$’000) |
| |||||||||
| | |
(audited)
|
| |
(audited)
|
| |
(audited)
|
| |||||||||
Total assets | | | | | 8,535,525 | | | | | | 6,379,290 | | | | | | 5,805,275 | | |
Total liabilities | | | | | 2,402,962 | | | | | | 1,995,935 | | | | | | 2,267,948 | | |
Net assets | | | | | 6,132,563 | | | | | | 4,383,355 | | | | | | 3,537,327 | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
Executive director
|
| |
Non-executive
director |
| |
Independent non-
executive directors |
|
Grantees
|
| |
Mr. Oyler
(Chairman and Chief Executive Officer) |
| |
Dr. Wang (Chair
of the Scientific Advisory Board) |
| |
Nine directors, namely
Dr. Brandicourt, Dr. Dugan, Mr. Glazer, Mr. Goller, Mr. Hooper, Mr. Krishana, Dr. Riva, Dr. Sanders, and Mr. Yi |
|
Grant date fair value | | | | | | | | | | |
— Proposed RSU Grants | | | US$6,000,000 | | | US$1,333,333 | | | US$200,000 each, totaling US$1,800,000 |
|
— Proposed PSU Grant | | | US$6,000,000 | | | — | | | — | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
2016 Plan
|
| |
Outstanding number
|
| |
Available for future grants
|
| ||||||
RSUs
|
| | | | 65,397,709 | | | | | | 37,064,832 | | |
PSUs | | | | | 0 | | | ||||||
Options | | | | | 60,637,471 | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
Executive director
|
| |
Non-executive
director |
| |
Independent non-executive
directors |
|
Grantees
|
| |
Mr. Oyler (Chairman
and Chief Executive Officer) |
| |
Dr. Wang
(Chair of the Scientific Advisory Board) |
| |
Nine directors, namely
Dr. Brandicourt, Dr. Dugan, Mr. Glazer, Mr. Goller, Mr. Hooper, Mr. Krishana, Dr. Riva, Dr. Sanders, and Mr. Yi |
|
Grant date fair value | | | | | | | | | | |
— Proposed RSU Grants | | | US$6,000,000 | | | US$1,333,333 | | | US$200,000 each, totaling US$1,800,000 | |
— Proposed PSU Grant | | | US$6,000,000 | | | — | | | — | |
Indicative number of units (based on the closing price of US$159.23 per ADS of the Company on Nasdaq (or US$12.25 per ordinary share) on the assumed grant date which is April 1, 2024 | | |||||||||
— RSUs | | | 489,853 | | | 108,849 | | | 16,328 each, totaling 146,952 | |
— PSUs | | | 489,853 | | | — | | | — | |
Vesting schedule | | | | | | | | | | |
— Proposed RSU Grants | | | 25% of the ordinary shares shall vest on each anniversary of the grant date, subject to continued service; provided, however, that upon a termination without cause or for good reason as defined in Mr. Oyler’s employment agreement, the RSUs shall become vested as if he had remained employed for an additional 20 months; provided further that the RSUs shall become fully vested for underlying shares upon a change in control of the Company or death or disability. | | | 25% of the ordinary shares shall vest on each anniversary of the grant date, subject to continued service; provided that the RSUs shall become fully vested for underlying shares upon death or disability | | | 100% of the ordinary shares shall vest upon the earlier to occur of the first anniversary of the grant date or the date of the next annual general meeting of shareholders; provided, however, that all vesting shall cease if the director resigns from the Board or otherwise ceases to serve as a director other than as set forth below or the Board determines that the circumstances warrant continuation of vesting. Unvested RSUs shall accelerate in full upon (i) death, (ii) disability, (iii) termination of service in connection with a change of control of the Company, or (iv) upon a change of control of the Company if the director’s service continues and the awards are not assumed by | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
Executive director
|
| |
Non-executive
director |
| |
Independent non-executive
directors |
|
Grantees
|
| |
Mr. Oyler (Chairman
and Chief Executive Officer) |
| |
Dr. Wang
(Chair of the Scientific Advisory Board) |
| |
Nine directors, namely
Dr. Brandicourt, Dr. Dugan, Mr. Glazer, Mr. Goller, Mr. Hooper, Mr. Krishana, Dr. Riva, Dr. Sanders, and Mr. Yi |
|
| | | | | | | | | the acquiror at the time of the change of control. Subject to specific terms and conditions designed for compliance with applicable tax and other regulations, a director generally may elect to defer settlement of their RSUs until six months following the date that the director ceases to serve as a director. | |
— Proposed PSU Grant | | | The ordinary shares shall cliff vest at the end of a three-year performance period once the total revenue number for the third year is finalized to the extent the performance metrics are met, subject to continued service; provided, however, that upon a termination without cause or for good reason as defined in Mr. Oyler’s employment agreement, the PSUs with completed performance periods shall become vested and paid out based on actual performance while the awards for incomplete years will be paid out at target as if he had remained employed for an additional 20 months; provided further that the PSUs shall become fully vested for underlying shares upon a change in control of the Company or death or disability pursuant to the same formula. | | | — | | | — | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Comparable Companies |
| |
Headquarters
|
| |
Stock code
|
| |
Year of
incorporation |
| |
Market
capitalization as of the date of Announcement |
| |
Revenue
(Note 1)
|
| |
Research and
development expenses
(Note 1)
|
| |
No. of
employees (Note 3) |
| |
Description
|
| ||||||||||||
| | | | | | | | | | | | | | | | | |
(US$ million)
(Note 2)
|
| |
(US$ million)
(Note 2)
|
| | | | | | | | | | ||||||
WuXi AppTec Co., Ltd. |
| | China | | |
2359 HK Equity
603259
Shanghai Stock Exchange (SSE) Equity |
| | | | 2000 | | | |
HK$[142.06]
billion (equivalent to US$[18.16] billion) |
| | | | 5,581 | | | | | | 199 | | | | | | 41,116 | | | |
WuXi AppTec Co., Ltd.
manufactures medical products. The Company produces biological agents, antibodies, biological diagnostic reagents, and other products. WuXi AppTec Co., Ltd. also provides biological analysis, technical study, and other services. |
|
Alnylam Pharmaceuticals, Inc.
|
| |
United States
|
| | ALNY US Equity | | | | | 2002 | | | |
US$[18.9]
billion (equivalent to HK$[147.6] billion) |
| | | | 1,828 | | | | | | 1,004 | | | | | | 2,100 | | | |
Alnylam Pharmaceuticals, Inc.
operates as an early-stage therapeutics company. The Company discovers and develops drug and medicines for the treatment of human disease. Alnylam Pharmaceuticals serves health care sectors in the United States and the United Kingdom. |
|
Biogen Inc. | | |
United States
|
| | BIIB US Equity | | | | | 1978 | | | |
US$[32.5]
billion (equivalent to HK$[253.8) billion) |
| | | | 9,836 | | | | | | 2,462 | | | | | | 7,570 | | | |
Biogen Inc. develops,
manufactures, and commercializes therapies, focusing on neurology, oncology, and immunology. The Company products address diseases such as multiple sclerosis, non-hodgkin’s lymphoma, rheumatoid arthritis, crohn’s disease, and psoriasis. |
|
Biomarin Pharmaceutical Inc. | | |
United States
|
| | BMRN US Equity | | | | | 1997 | | | |
US$[16.2]
billion (equivalent to HK$[126.8] billion) |
| | | | 2,419 | | | | | | 747 | | | | | | 3,401 | | | |
BioMarin Pharmaceutical Inc.
develops and commercializes therapeutic enzyme products. The Company has applied its proprietary enzyme technology to develop products for lysosomal storage diseases and for the treatment of serious burns. BioMarin Pharmaceutical through its subsidiaries provides analytical and diagnostic products and services in the area of carbohydrate biology. |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Comparable Companies |
| |
Headquarters
|
| |
Stock code
|
| |
Year of
incorporation |
| |
Market
capitalization as of the date of Announcement |
| |
Revenue
(Note 1)
|
| |
Research and
development expenses
(Note 1)
|
| |
No. of
employees (Note 3) |
| |
Description
|
| ||||||||||||
| | | | | | | | | | | | | | | | | |
(US$ million)
(Note 2)
|
| |
(US$ million)
(Note 2)
|
| | | | | | | | | | ||||||
Charles River Laboratories Inc | | |
United States
|
| | CRL US Equity | | | | | 1947 | | | |
US$[13.7]
billion (equivalent to HK$[107.2] billion) |
| | | | 4,129 | | | |
36 (Note 4)
|
| | | | 21,800 | | | |
Charles River Laboratories
International, Inc. provides research tools and support services for drug discovery and development. The Company offers animal research models in research and development for new drugs, devices, and therapies. Charles River Laboratories International serves pharmaceutical and biotechnology companies, hospitals, and academic institutions worldwide. |
| |||
Illumina, Inc. | | |
United States
|
| | ILMN US Equity | | | | | 1988 | | | |
US$[21.5]
billion (equivalent to HK$[168.3] billion) |
| | | | 4,504 | | | | | | 1,354 | | | | | | 10,670 | | | |
Illumina, Inc. develops,
manufactures and markets integrated systems for the large scale analysis of genetic variation and biological function. The Company provides a comprehensive line of products and services that currently serve the sequencing, genotyping and gene expression markets for genomic research centers, pharmaceutical companies, academic institutions and biotechnology companies. |
|
Incyte Corporation
|
| |
United States
|
| | INCY US Equity | | | | | 2002 | | | |
US$[13.5]
billion (equivalent to HK$[105.4] billion) |
| | | | 3,696 | | | | | | 1,628 | | | | | | 2,524 | | | |
Incyte Corporation is a biopharmaceutical company. The Company discovers, develops, and commercializes proprietary small molecule drugs, primarily used in oncology.
|
|
Moderna, Inc. | | |
United States
|
| | MRNA US Equity | | | | | 2010 | | | |
US$[39.4]
billion (equivalent to HK$[307.8] billion) |
| | | | 6,848 | | | | | | 4,845 | | | | | | 5,600 | | | |
Moderna, Inc. operates as a
biotechnology company. The Company focuses on the discovery and development of messenger RNA therapeutics and vaccines. Moderna develops mRNA medicines for infectious, immuno-oncology, and cardiovascular diseases. |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Comparable Companies |
| |
Headquarters
|
| |
Stock code
|
| |
Year of
incorporation |
| |
Market
capitalization as of the date of Announcement |
| |
Revenue
(Note 1)
|
| |
Research and
development expenses
(Note 1)
|
| |
No. of
employees (Note 3) |
| |
Description
|
| ||||||||||||
| | | | | | | | | | | | | | | | | |
(US$ million)
(Note 2)
|
| |
(US$ million)
(Note 2)
|
| | | | | | | | | | ||||||
Neurocrine Biosciences, Inc. | | |
United States
|
| | NBIX US Equity | | | | | 1992 | | | |
US$[13.9]
billion (equivalent to HK$[108.3] billion) |
| | | | 1,887 | | | | | | 565 | | | | | | 1,400 | | | |
Neurocrine Biosciences, Inc. is
focused on the discovery and development of therapeutics for neuropsychiatric, neuroinflammatory, and neurodegenerative diseases and disorders. The Company is developing therapeutic interventions for anxiety, depression, alzheimer’s disease, insomnia, stroke, malignant brain tumors, multiple sclerosis, obesity, and diabetes. |
|
The Company | | |
China/United
States/ Switzerland |
| |
BGNE (Nasdaq)
6160 (Main Board)
688235 (STAR Market)
|
| | | | 2010 | | | |
US$[28.47]
billion (equivalent to HK$[223.45] billion) |
| | | | 2,458.78 | | | | | | 1,778.59 | | | | | | 10,708 | | | |
The Company is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide.
|
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
WuXi AppTec Co., Ltd. | | |
2022 (Note 1)
|
| | Directors, supervisor, senior management, mid-level manager, basic-level manager, backbone member of technicians, other technicians, who is a full-time PRC or non-PRC employee of any members of the group | | | H share award and trust scheme (PSU) | | | In order to attract, motivate and retain skilled and experienced personnel to strive for the future development and expansion of the group by providing them with the opportunity to be further incentivized by equity interests in the company, more directly associated with the equity performance of the company, modernize the company’s renumeration practices and to better align with the interests of the shareholders, while seeking a balanced approach in the operational and executive management oversight. | | | Yes, if there is an event of change in control (as defined under the Hong Kong Code on Takeovers and Mergers) of the company by way of a merger, a privatization of the company by way of a scheme or by way of an offer, change of actual control of the company involving reorganization of major assets, the company no longer exists after merger with another company, or division of the company. | | | The awarded H Shares have four vesting period, with (i) 0%, 25%, 25% and 50% or (ii) 25%, 25%, 25% and 25% of the awards within the year immediately following the first, second, third and fourth anniversary date of the grant date upon meeting certain annual performance conditions. | | | No specific clawback terms. | |
Alnylam Pharmaceuticals, Inc. | | | 2022 | | | Employees, officers and directors | | | Stock options, restricted stock and RSUs (together, restricted stock awards), stock appreciation rights and other | | | To advance the interests of the company’s stockholders by enhancing the company’s ability to attract, retain and motivate | | | Yes, the board may at any time provide that any award shall become immediately exercisable in full or in part, free of | | | RSUs granted to employees generally vest over a three-year period, with one-third of the shares vesting on each of the three successive | | | No specific clawback terms, provided the plan is subject to the company’s clawback policies in effect from time to time. | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | stock-based awards, and has a fungible share pool | | | persons who are expected to make important contributions to the company by providing such persons with equity ownership opportunities and performance-based incentives that are intended to better align the interests of such persons with those of the company’s stockholders. | | | some or all restrictions or conditions, or otherwise realizable in full or in part, as the case may be. | | |
anniversaries of the grant date.
PSUs granted in 2023 and 2022 will vest upon the later of the one-year anniversary of the date of grant and the achievement of specific clinical development, regulatory, commercial and/or financial performance events, as approved by our people, culture and compensation committee.
|
| | | |
Biogen Inc. | | | 2022 for non-employee directors equity plan; and 2017 for omnibus equity plan (collectively as one equity plan in this analysis) | | | Non-employee directors for non-employee directors equity plan; and employees for omnibus equity plan | | | Stock options, shares of restricted stock, RSUs, stock appreciation rights and other awards for non-employee directors equity plan; and stock options, shares of restricted stock, RSUs, performance shares, stock appreciation rights and other awards for omnibus equity plan | | | Non-employee directors equity plan is to provide an additional incentive to those directors to promote the success of the company and its affiliates for non-employee directors equity plan. Omnibus equity plan is to attract and retain employees of the company and its affiliates, to provide an incentive for them to generate stockholder value by contributing to the appreciation of the company’s stock price and to enable them to participate in the | | | Yes, for non-employee directors equity plan, the committee appointed to administer of the plan may (a) accelerate the date on which any award granted under the plan becomes exercisable or (b) accelerate the Vesting Date or waive or adjust any condition imposed hereunder with respect to the vesting or exercisability of an award, provided that the committee determines that such acceleration, | | |
RSUs awarded to employees generally vest no sooner than one-third per year over three years on the anniversary of the date of grant, or upon the third anniversary of the date of the grant, provided the employee remains continuously employed with us, except as otherwise provided in the plan.
RSUs awarded to director for service on the board of directors vest on the first anniversary of the date of grant, provided in each case that the director continues to serve the board of directors through
|
| | No specific clawback terms for non-employee directors equity plan. For omnibus equity plan, the compensation committee may cancel, rescind, withhold, or otherwise limit or restrict awards if a participant is not in compliance with the provisions of the plan or engages in certain detrimental activities. In addition, the compensation committee may provide that awards and related proceeds are subject to forfeiture or | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | growth of the company by granting awards with respect to the company’s stock. | | | waiver or other adjustment is necessary or desirable in light of extraordinary circumstances. For omnibus equity plan, accelerated vesting includes certain terminations of employment, certain transactions, including a corporate change in control, or in the participant’s award agreement. | | |
the vesting date.
PSUs awarded to employees have three performance periods and vest on the third anniversary of the grant date.
|
| | disgorgement to the extent required or permitted by applicable company policy, law or stock exchange listing standards. | |
Biomarin Pharmaceutical Inc. | | | 2023 | | | Employees, directors and consultants | | | Incentive stock options, non-statutory stock options, stock appreciation rights, restricted stock awards, RSUs, performance stock awards, performance cash awards, and other stock awards | | | To help the company secure and retain the services of eligible award recipients, provide incentives for such persons to exert maximum efforts for the success of the company and any affiliate, and provide a means by which the eligible recipients may benefit from increases in value of the common stock. | | | Yes, the board will have power to accelerate the vesting in whole or in part. The plan may be subject to additional acceleration of vesting and exercisability upon or after a change in control. | | |
RSUs granted to employees generally vest annually over a straight-line four-year period after the grant date.
RSUs with performance-based, which is a kind of PSUs in substance, the vesting conditions generally vest over a three-year period on a cliff basis three years after the grant date.
RSUs with market-based vesting conditions vest, if at all, in full following a three-year service period only if certain total shareholder return results relative to the Nasdaq Biotechnology Index
|
| | The board may impose clawback terms, recovery or recoupment provisions as the board determines necessary or appropriate, including but not limited to a reacquisition right in respect of previously acquired shares of common stock or other cash or property upon the occurrence of an event constituting cause. No recovery of compensation under such a clawback policy will be an event giving rise to a right to resign for “good reason” or “constructive termination” (or | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | | | | | | | comparative companies are achieved. | | | similar term). The plan will also be subject to recoupment in accordance with any clawback policy that the company is required to adopt pursuant to the listing standards of any national securities exchange or association on which the company’s securities are listed or as is otherwise required by the Dodd-Frank Wall Street Reform and Consumer Protection Act or other applicable law. | |
Charles River Laboratories Inc | | | 2023 | | | Key employees, directors and other individuals or entities providing services to the company or its affiliates who, in the opinion of the administrator, are in a position to make a significant contribution to the success of the company and its affiliates | | | Stock options, SARs, restricted stock, unrestricted stock, deferred stock, cash performance award, other performance awards | | | To reward performance and create incentives to meet long-term objectives. Because the committee particularly values long-term shareholder value creation, it targets long-term equity incentives to provide total compensation opportunities that, if achieved, would result in market competitive pay levels for the | | | Yes, the administrator shall have the authority unilaterally to accelerate or delay a payment upon the death of the participant or if an employee terminates due to death more than 12 months following the date of grant of a PSU, a pro rata portion of the PSU is deemed to immediately vest. | | |
RSUs principally vest over 4 years and generally vest in instalments on or about the anniversary date in each of the four years following the date of grant, subject to continued employment. The instalments are generally equivalent in amount.
PSUs vest from zero to a specified maximum and typically vest over 3 years.
|
| | The committee may determine that any award under the plan shall be subject to provisions for the forfeiture and/or reimbursement of all amounts received in connection with an award in the event of breach of noncompetition, nonsolicitation or confidentiality agreements. All awards granted under the plan are subject to recoupment, to | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | executives. | | | | | | | | | the extent applicable, under the company’s corporate governance guidelines, as may be revised from time to time, and/or any other recoupment, clawback or similar policy that may be approved by the board or any committee thereof. | |
Illumina, Inc. | | | 2023 | | | Officers and inside directors for stock options, stock awards and cash awards | | | Stock options, stock awards, cash awards, stock appreciation rights | | | To attract and retain the best available personnel for positions of substantial responsibility, to provide additional incentive to service providers, and to promote the success of the company’s business. | | | Yes, the administrator shall have the authority, in its discretion, accelerate the vesting in the event of a participant’s death or disability. | | |
RSUs generally vest over a four-year period with equal vesting annually.
PSUs generally vest over a three-year performance period is based on the company’s performance relative to specified earnings per share targets and continued employment through the vesting period.
|
| | All awards granted under the plan will be subject to recoupment in accordance with any clawback policy adopted by company or as the administrator determines necessary or appropriate. The plan will also be subject to recoupment in accordance with any clawback policy that the company is required to adopt pursuant to the listing standards of any national securities exchange or association on which the company’s securities are listed or as is otherwise required by the | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | | | | | | | | | | Dodd-Frank Wall Street Reform and Consumer Protection Act or other applicable laws. | |
Incyte Corporation
|
| | 2023 | | | Employees, non-employee directors, consultants and scientific advisors | | | Stock options, RSUs and PSUs | | | To promote the long-term success of the corporation and the creation of stockholder value by (a) encouraging employees, outside directors and consultants to focus on critical long-range objectives, (b) encouraging the attraction and retention of employees, outside directors and consultants with exceptional qualifications and (c) linking employees, outside directors and consultants directly to stockholder interests through increased stock ownership. | | | Yes, in the event of the participant’s death, total and permanent disability or retirement or other events. | | |
RSUs granted to employees generally vest annually over a straight-line four-year period after the grant date.
PSUs granted to employees generally vest with performance and/or service-based milestones with graded and/or cliff vesting over three to four years.
|
| | No specific clawback terms. | |
Moderna, Inc. | | | 2018 | | | Officers, employees, non-employee directors and consultants | | | Stock options, RSUs and PSUs | | | To encourage and enable the participants to acquire a proprietary interest in the company. | | | Yes, the administrator may at any time accelerate the vesting schedule specified. | | | RSUs are service based awards that generally vest over a four-year period, with the first 25% of such awards vesting following twelve months of continued employment or service. The remaining awards | | | No specific clawback terms provided the plan is subject to the company’s clawback policies ineffect from time to time. | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | | | | | | |
vest in twelve quarterly instalments over the following twelve quarters.
PSUs are contingent upon the achievement of specified preestablished goals over the performance period, generally three years.
|
| | | |
Neurocrine Biosciences, Inc. | | | 2023 | | | Employees, directors and consultants | | | Incentive stock options, non-statutory stock options, stock appreciation rights, restricted stock awards, restricted stock unit awards, performance awards, and other awards. | | | To secure and retain the services of employees, directors and consultants, to provide incentives for such persons to exert maximum efforts for the success of the company and its affiliates, and to provide a means by which such persons may be given an opportunity to benefit from increases in the value of the company’s common stock. | | | Yes, in the event a transaction in which the acquiring entity does not assume or continue outstanding awards or substitute similar awards for outstanding awards. | | |
RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees.
Performance-based restricted stock units (PRSUs) vest based on the achievement of certain predefined company-specific performance criteria. Any unvested PRSUs will expire if it is determined the related performance criteria has not been met during the applicable three to four-year performance period.
|
| | The board may impose clawback terms, recovery or recoupment provisions as the board determines necessary or appropriate, including but not limited to a reacquisition right in respect of previously acquired shares of common stock or other cash or property upon the occurrence of an event constituting cause. No recovery of compensation under such a clawback policy will be an event giving rise to a right to resign for “good reason” or “constructive termination” (or similar term). The plan will also be subject to recoupment in accordance with | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | | | | | | | | | | any clawback policy that the company is required to adopt pursuant to the listing standards of any national securities exchange or association on which the company’s securities are listed or as is otherwise required by the Dodd-Frank Wall Street Reform and Consumer Protection Act or other applicable law. | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
The Company (2016 Plan) |
| | 2022 | | | Officers, employees, non-employee directors and consultants of the Company | | | Share options, RSUs, PSUs and other incentive awards | | | To encourage and enable the officers, employees, nonemployee directors and consultants of the Group upon whose judgment, initiative and efforts the Company largely depends for the successful conduct of its businesses to acquire a proprietary interest in the Company | | | Yes, the administrator has the authority to accelerate vesting in circumstances involving death, disability, retirement, termination or a change in control. | | |
With regards to RSUs, 25% of the ordinary shares shall vest on each anniversary of the grant date, subject to continued service for executive director and certain non-executive directors; and 100% of the ordinary shares shall vest upon the earlier to occur of the first anniversary of the grant date and the next annual general meeting for certain non-executive directors.
With regards to PSUs, the ordinary shares shall cliff vest at the end of the three-year performance period once the total revenue number for the third year is finalized to the extent the performance metrics are met, subject to continued service; provided, however, that upon a termination without cause or for good reason as defined in Mr. Oyler’s employment agreement, the PSUs with completed
|
| | No specific clawback terms, provided Mr. Oyler’s RSU and PSU grants are subject to the Company’s clawback policy. | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company name
(Plan name) |
| |
Latest year
of adoption / restatement/ amendment |
| |
Participants
|
| |
Type of
award(Note 2) |
| |
Purpose
of the grant |
| |
Accelerated
vesting according to the respective latest publications |
| |
Vesting terms
of the RSUs / PSUs according to the respective latest publications |
| |
Specific
clawback terms for the RSUs / PSUs granted to non-employee directors according to the respective latest publications |
|
| | | | | | | | | | | | | | | | | | performance periods shall become vested and paid out based on actual performance while the awards for incomplete years will be paid out at target as if he had remained employed for an additional 20 months; provided further that the PSUs shall become fully vested for underlying shares upon a change in control of the Company pursuant to the same formula. | | | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Grantee
|
| |
Position(s)
|
| |
Total
cash and other non-equity emoluments for the year ended December 31, 2023
(Note 1)
(US$)
|
| |
Total
grant date fair value of RSU and PSU grants
(Note 2)
(US$)
|
| |
Total
grant date fair value of share option grants
(Note 2)
(US$)
|
| |
Aggregate
remuneration (US$) |
| ||||||||||||
Mr. Oyler | | | Chairman, Executive Director and Chief Executive Officer |
| | | | 2,406,992 | | | | | | 12,000,000 | | | | | | 6,000,000 | | | | | | 20,406,992 | | |
Dr. Wang | | | Non-executive Director | | | | | 416,937 | | | | | | 1,333,333 | | | | | | 2,666,667 | | | | | | 4,416,937 | | |
Dr. Brandicourt | | |
Independent Non-executive Director
|
| | | | — | | | | | | 200,000 | | | | | | 200,000 | | | | | | 400,000 | | |
Mr. Dugan | | |
Independent Non-executive Director
|
| | | | 110,750 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 510,750 | | |
Dr. Glazer | | |
Independent Non-executive Director
|
| | | | 81,000 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 481,000 | | |
Mr. Goller | | |
Independent Non-executive Director
|
| | | | 82,125 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 482,125 | | |
Mr. Hooper | | |
Independent Non-executive Director
|
| | | | 113,356 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 513,356 | | |
Mr. Krishana | | |
Independent Non-executive Director
|
| | | | 84,250 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 484,250 | | |
Mr. Malley | | |
Independent Non-executive Director
|
| | | | 100,769 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 500,769 | | |
Dr. Riva | | |
Independent Non-executive Director
|
| | | | 91,875 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 491,875 | | |
Dr. Sanders | | |
Independent Non-executive Director
|
| | | | 101,750 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 501,750 | | |
Mr. Yi | | |
Independent Non-executive Director
|
| | | | 87,250 | | | | | | 200,000 | | | | | | 200,000 | | | | | | 487,250 | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Comparable Companies
|
| |
Stock code
|
| |
Market
Capitalization as of the date of Announcement
(Note)
|
| |
Total Remunerations (US$’000)
|
| |||||||||||||||||||||
|
Executive and
non-executive directors |
| |
Independent directors
|
| ||||||||||||||||||||||||||
|
Minimum
|
| |
Maximum
|
| |
Minimum
|
| |
Maximum
|
| ||||||||||||||||||||
WuXi AppTec Co., Ltd. | | | 2359 HK Equity | | | HK$[171.9] billion (equivalent to US$[22.0] billion) |
| | | | 731 | | | | | | 7,776 | | | | | | 56 | | | | | | 56 | | |
Alnylam Pharmaceuticals, Inc. |
| | ALNY US Equity | | | US$[18.9] billion (equivalent to HK$[147.6 ] billion) |
| | | | 2,422 | | | | | | 5,408 | | | | | | 474 | | | | | | 620 | | |
Biogen Inc. | | | BIIB US Equity | | | US$[32.5] billion (equivalent to HK$[253.8] billion) |
| | | | 4,930 | | | | | | 30,489 | | | | | | 272 | | | | | | 667 | | |
Biomarin Pharmaceutical Inc. |
| | BMRN US Equity | | | US$[16.2] billion (equivalent to HK$[126.8 ] billion) |
| | | | 5,189 | | | | | | 18,352 | | | | | | 405 | | | | | | 500 | | |
Charles River Laboratories Inc | | | CRL US Equity | | | US$[13.7] billion (equivalent to HK$[107.2 ] billion) |
| | | | 5,107 | | | | | | 18,352 | | | | | | 319 | | | | | | 369 | | |
Illumina, Inc. | | | ILMN US Equity | | | US$[21.5] billion (equivalent to HK$[168.3 ] billion) |
| | | | 3,538 | | | | | | 26,752 | | | | | | 311 | | | | | | 465 | | |
Incyte Corporation | | | INCY US Equity | | | US$[13.5] billion (equivalent to HK$[105.4 ] billion) |
| | | | 4,625 | | | | | | 16,669 | | | | | | 295 | | | | | | 495 | | |
Moderna, Inc. | | | MRNA US Equity | | | US$[39.4 ] billion (equivalent to HK$[307.8 ] billion) |
| | | | 6,074 | | | | | | 19,364 | | | | | | 453 | | | | | | 534 | | |
Neurocrine Biosciences, Inc. | | | NBIX US Equity | | | US$[13.9 ] billion (equivalent to HK$[108.3 ] billion) |
| | | | 4,924 | | | | | | 11,903 | | | | | | 460 | | | | | | 497 | | |
The Company | | | BGNE (Nasdaq) 6160 (Main Board) 688235 (STAR Market) 6160 HK Equity |
| | US$[21.5] billion (equivalent to HK$[168.3 ] billion) |
| | | | 4,049 | | | | | | 20,407 | | | | | | 481 | | | | | | 513 | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
Company
|
| |
Executive and
non-executive directors RSU and PSU grants (% Total) |
| |
Independent
non-executive directors RSU and PSU grants (% Total) |
| ||||||
Wuxi AppTec Co., Ltd. | | | | | 35.3% | | | | | | 0.0% | | |
Alnylam Pharmaceuticals, Inc. | | | | | 11.9% | | | | | | 83.0% | | |
Biogen Inc. | | | | | 64.2% | | | | | | 64.1% | | |
Biomarin Pharmaceutical Inc. | | | | | 71.1% | | | | | | 82.6% | | |
Charles River Laboratories Inc | | | | | 66.8% | | | | | | 37.6% | | |
Illumina, Inc. | | | | | 51.9% | | | | | | 4.6% | | |
Incyte Corporation | | | | | 60.8% | | | | | | 43.2% | | |
Moderna, Inc. | | | | | 29.6% | | | | | | 7.5% | | |
Neurocrine Biosciences, Inc. | | | | | 45.3% | | | | | | 0.0% | | |
Maximum | | | | | 71.1% | | | | | | 83.0% | | |
Minimum | | | | | 11.9% | | | | | | 0.0% | | |
Median | | | | | 51.9% | | | | | | 37.6% | | |
Average | | | | | 48.5% | | | | | | 35.8% | | |
The Company (Note)
|
| | | | 48.3% | | | | | | 40.4% | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
| | |
Latest Practicable Date
|
| |
Assuming full vesting or target vesting
of the Proposed Equity Grants |
| ||||||||||||||||||
| | |
No. of shares
|
| |
%
|
| |
No. of shares
|
| |
%
|
| ||||||||||||
Mr. Oyler
|
| | | | 74,879,026 | | | | | | 5.51% | | | | | | 75,858,732 | | | | | | 5.57% | | |
Dr. Wang
|
| | | | 20,313,993 | | | | | | 1.49% | | | | | | 20,422,842 | | | | | | 1.50% | | |
Dr. Brandicourt
|
| | | | 27,794 | | | | | | 0.002% | | | | | | 44,122 | | | | | | 0.003% | | |
Dr. Dugan
|
| | | | 113,815 | | | | | | 0.008% | | | | | | 130,143 | | | | | | 0.01% | | |
Mr. Glazer
|
| | | | 3,108,659 | | | | | | 0.23% | | | | | | 3,124,987 | | | | | | 0.23% | | |
Mr. Goller
|
| | | | 453,232 | | | | | | 0.03% | | | | | | 469,560 | | | | | | 0.03% | | |
Mr. Hooper
|
| | | | 183,885 | | | | | | 0.01% | | | | | | 200,213 | | | | | | 0.01% | | |
Mr. Krishana
|
| | | | 453,232 | | | | | | 0.03% | | | | | | 469,560 | | | | | | 0.03% | | |
Dr. Riva
|
| | | | 113,815 | | | | | | 0.008% | | | | | | 130,143 | | | | | | 0.01% | | |
Dr. Sanders
|
| | | | 136,500 | | | | | | 0.01% | | | | | | 152,828 | | | | | | 0.01% | | |
Mr. Yi
|
| | | | 436,150 | | | | | | 0.03% | | | | | | 452,478 | | | | | | 0.03% | | |
Other Shareholders
|
| | | | 1,259,304,268 | | | | | | 92.63% | | | | | | 1,259,304,268 | | | | | | 92.54% | | |
Total | | | | | 1,359,524,369 | | | | | | 100.00% | | | | | | 1,360,759,876 | | | | | | 100.00% | | |
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
PROPOSALS 11 — 14. PROPOSED GRANTS OF RESTRICTED SHARE UNITS AND
PERFORMANCE SHARE UNITS |
|
|
Brandon Li
|
| |
Karl Chan
|
|
|
Director
|
| |
Director
|
|
|
Proposal 11. Approval of the RSU Grant to Mr. Oyler
|
|
|
The Board of Directors recommends that shareholders vote FOR approval of the Proposed RSU Grant to Mr. Oyler and transactions contemplated therein.
|
|
|
Proposal 12. Approval of the PSU Grant to Mr. Oyler
|
|
|
The Board of Directors recommends that shareholders vote FOR approval of the Proposed PSU Grant to Mr. Oyler and transactions contemplated therein.
|
|
|
Proposal 13. Approval of the RSU Grants to Dr. Wang
|
|
|
The Board of Directors recommends that shareholders vote FOR approval of the Proposed RSU Grant to Dr. Wang and transactions contemplated therein.
|
|
|
Proposal 14. Approval of the RSU Grants to the
Independent Non-Executive Directors |
|
|
Proposal 14. Approval of the RSU Grants to the Independent
Non-Executive Directors |
|
|
The Board of Directors recommends that shareholders vote FOR approval of the Proposed RSU Grants to Dr. Brandicourt, Dr. Dugan, Mr. Glazer, Mr. Goller, Mr. Hooper, Mr. Krishana, Dr. Riva, Dr. Sanders and Mr. Yi and transactions contemplated therein.
|
|
|
Proposal 15. Non-Binding, Advisory Vote on
Executive Compensation |
|
|
The Board of Directors recommends that shareholders vote FOR approval, on a non-binding, advisory basis, of the compensation of our named executive officers.
|
|
|
Proposal 16. Non-Binding, Advisory Vote on the
Frequency of Advisory Votes on Executive Compensation |
|
|
The Board of Directors recommends that shareholders vote FOR approval, on a non-binding, advisory basis, of the holding of an advisory vote on the compensation of our named executive officers every year.
|
|
|
Proposal 17. Approval of the Third Amended and
Restated 2016 Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
| | |
2023
|
| |
2022
|
| ||||||||
Number of Employees (beginning of year) | | | | | 9,212 | | | | | | | 8,033 | | | |
Number of Employees (end of year) | | | | | 10,473 | | | | | | | 9,212 | | | |
Total Number of New Employees (net)
|
| | | | 1,261 | | | | | | | 1,179 | | | |
Percentage Increase | | | | | 13.69 | % | | | | | | 14.68 | % | | |
| | |
2023
|
| |
2022
|
| ||||||||
Share Options Granted | | | | | 9,817,925 | | | | | | | 12,516,816 | | | |
Time-Based Full Value Shares and Units Granted | | | | | 34,573,994 | | | | | | | 38,707,669 | | | |
Total Awards Granted(1)
|
| | | | 44,391,919 | | | | | | | 51,224,485 | | | |
Weighted-Average Ordinary Shares Outstanding During the Fiscal Year | | | | | 1,357,034,547 | | | | | | | 1,340,729,572 | | | |
Annual Burn Rate | | | | | 3.3 | % | | | | | | 3.8 | % | | |
Two-Year Average Burn Rate | | | | | 3.5 | % | | | | | | | | | |
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
| | |
Share Awards (RSUs/PSUs)
|
| |
Options
|
| ||||||||||||||||||
Name and Position
|
| |
Dollar Value
(US$) |
| |
Number of
Ordinary Shares |
| |
Dollar Value
(US$) |
| |
Number of
Ordinary Shares |
| ||||||||||||
John V. Oyler, Co-Founder, Chairman and Chief Executive Officer | | | | $ | 12,000,000 | | | | |
|
(1)
|
| | | | $ | 6,000,000 | | | | |
|
(1)
|
| |
Dr. Xiaobin Wu, President, Chief Operating Officer and General Manager of China | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Julia Wang, Chief Financial Officer | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
| | |
Share Awards (RSUs/PSUs)
|
| |
Options
|
| ||||||||||||||||||
Name and Position
|
| |
Dollar Value
(US$) |
| |
Number of
Ordinary Shares |
| |
Dollar Value
(US$) |
| |
Number of
Ordinary Shares |
| ||||||||||||
Dr. Lai Wang, Global Head of R&D | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Chan Lee, Senior Vice President, General Counsel and Assistant Secretary |
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
All current executive officers, as a group | | | | $ | 12,000,000 | | | | |
|
(1)
|
| | | | $ | 6,000,000 | | | | |
|
(1)
|
| |
All current non-employee directors, as a group | | | | $ | 1,800,000 | | | | |
|
(1)
|
| | | | $ | 1,800,000 | | | | |
|
(1)
|
| |
All employees who are not executive officers, as a group | | | | $ | 1,333,333 | | | | |
|
(1)
|
| | | | $ | 2,666,667 | | | | |
|
(1)
|
| |
Plan Category
|
| |
Number of Securities
to Be Issued Upon Exercise of Outstanding Options, Warrants and Rights (#Ordinary Shares) |
| |
Weighted-average
Exercise Price of Outstanding Option, Warrants and Rights(1) |
| |
Number of Securities
Remaining Available for Future Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column(a)) (#Ordinary Shares) |
| ||||||||||||
Equity compensation plans approved by security holders | | | | | 127,917,783 | (2) | | | | | | US$11.36 | | | | | | | 39,516,547 | (3) | | |
Equity compensation plans not approved by security holders | | | | | 16,628,353 | (4) | | | | | | US$0.55 | | | | | | | — | | | |
Total | | | | | 144,546,136 | | | | | | | — | | | | | | | 39,516,547 | | | |
|
Proposal 17. Approval of the Third Amended and Restated 2016
Share Option and Incentive Plan |
|
|
The Board of Directors recommends that shareholders vote FOR (a) the approval of the Third Amended and Restated 2016 Share Option and Incentive Plan and (b) conditional upon the passing of (a), the approval of the consultant sublimit set out therein.
|
|
|
Proposal 18. Approval of the Fourth Amended and
Restated Employee Share Purchase Plan |
|
|
Proposal 18. Approval of the Fourth Amended and Restated
Employee Share Purchase Plan |
|
|
Proposal 18. Approval of the Fourth Amended and Restated
Employee Share Purchase Plan |
|
|
The Board of Directors recommends that shareholders vote FOR the approval of the Fourth Amended and Restated 2018 Employee Share Purchase Plan.
|
|
|
Proposal 19. Adjournment Proposal
|
|
|
The Board of Directors recommends that shareholders vote FOR the approval of the Adjournment Proposal, if necessary, to solicit additional proxies.
|
|
|
Transaction of Other Business
|
|
|
Security Ownership of Certain Beneficial Owners and
Management |
|
Name of Beneficial Owner
|
| |
Number of
Ordinary Shares Beneficially Owned |
| |
Percentage of
Ordinary Shares Beneficially Owned |
| ||||||
5% or Greater Shareholders | | | | | | | | | | | | | |
Amgen Inc.(1) | | | | | 246,269,426 | | | | | | 18.11% | | |
Entities affiliated with Baker Bros. Advisors LP(2) | | | | | 138,678,037 | | | | | | 10.20% | | |
Entities affiliated with HHLR Advisors, Ltd.(3) | | | | | 142,888,241 | | | | | | 10.51% | | |
Entities affiliated with Capital International Investors(4) | | | | | 103,421,157 | | | | | | 7.61% | | |
Named Executive Officers and Directors | | | | | | | | | | | | | |
John V. Oyler(5) | | | | | 71,071,610 | | | | | | 5.14% | | |
Dr. Xiaobin Wu(6) | | | | | 3,767,647 | | | | | | * | | |
Julia Wang(7) | | | | | 589,420 | | | | | | * | | |
Dr. Lai Wang(8) | | | | | 3,398,842 | | | | | | * | | |
Chan Lee(9) | | | | | 105,209 | | | | | | * | | |
Dr. Olivier Brandicourt(10) | | | | | 27,794 | | | | | | * | | |
Dr. Margaret Dugan(11) | | | | | 73,918 | | | | | | * | | |
Donald W. Glazer(12) | | | | | 3,059,514 | | | | | | * | | |
| Security Ownership of Certain Beneficial Owners and Management | |
Name of Beneficial Owner
|
| |
Number of
Ordinary Shares Beneficially Owned |
| |
Percentage of
Ordinary Shares Beneficially Owned |
| ||||||
Michael Goller(13) | | | | | 413,335 | | | | | | * | | |
Anthony C. Hooper(14) | | | | | 143,988 | | | | | | * | | |
Ranjeev Krishana(15) | | | | | 413,335 | | | | | | * | | |
Dr. Alessandro Riva(16) | | | | | 73,918 | | | | | | * | | |
Dr. Corazon (Corsee) D. Sanders(17) | | | | | 96,603 | | | | | | * | | |
Dr. Xiaodong Wang(18) | | | | | 19,494,993 | | | | | | 1.42% | | |
Qingqing Yi(19) | | | | | 396,253 | | | | | | * | | |
All Directors and Executive Officers as a Group (15 persons)
|
| | | | 103,126,379 | | | | | | 7.37% | | |
| Security Ownership of Certain Beneficial Owners and Management | |
|
Executive Officers
|
|
Name
|
| |
Age
|
| |
Position(s)
|
|
John V. Oyler | | | 55 | | | Co-Founder, Chairman and Chief Executive Officer | |
Dr. Xiaobin Wu | | | 62 | | | President, Chief Operating Officer and General Manager, China | |
Julia Wang | | | 53 | | | Chief Financial Officer | |
Dr. Lai Wang | | | 47 | | | Global Head of R&D | |
Chan Lee | | | 56 | | | Senior Vice President, General Counsel and Assistant Secretary | |
| | | | |
Dr. Xiaobin Wu
|
| | | | |
| | | | | | | |
| Executive Officers | |
| |
|
| |
Julia Wang
|
| | | | |
| |
|
| | | | |
| | CHIEF FINANCIAL OFFICER OF BEIGENE, LTD. | | | |||||||
| |
|
| | |||||||
| |
Age: 53
Key Executive Since: June 2021 |
| | |
Experience:
|
| | |||
|
2021-Present:
|
| |
BeiGene, Ltd. (Chief Financial Officer)
|
| | |||||
|
2020-2021:
|
| | BeiGene, Ltd. (Senior Vice President, Enterprise Optimization and Deputy Chief Financial Officer) | | | |||||
|
2018-2020:
|
| | Alexion Pharmaceuticals (Senior Vice President of Global Business Finance and Corporate Planning) | | | |||||
|
2015-2018:
|
| | Quest Diagnostics (Vice President of U.S. Regional Finance and Enterprise Commercial; Vice President of Finance, Value Creation) | | | |||||
|
Prior:
|
| |
Johnson and Johnson (J&J) (Chief Financial Officer of various operating businesses) PepsiCo (Finance Initiatives Leader) |
| | |||||
|
Qualifications:
Ms. Wang received her B.A. in British Language and Literature from Shandong Normal University in 1992 and an MBA from Fuqua School of Business at Duke University in 1999. |
| | ||||||||
| |
|
| |
| |
|
| |
Dr. Lai Wang
|
| | | | |
| |
|
| | | | |
| | GLOBAL HEAD OF R&D OF BEIGENE, LTD. | | | |||||||
| |
|
| | |||||||
| |
Age: 47
Key Executive Since: April 2021 |
| | |
Experience:
|
| | |||
|
2011-Present:
|
| |
BeiGene, Ltd. (Global Head of R&D since 2021)
|
| | |||||
|
Prior:
|
| |
Joyant Pharmaceuticals (Director of Research)
|
| | |||||
|
Qualifications:
Dr. Wang received his B.S. from Fudan University in 1996 and a Ph.D. from the University of Texas Health Science Center at San Antonio in 2001. |
| | ||||||||
| |
|
| |
| Executive Officers | |
| | | | |
Chan Lee
|
| | | | |
| | | | | | | |
| | SENIOR VICE PRESIDENT, GENERAL COUNSEL AND ASSISTANT SECRETARY OF BEIGENE, LTD. | | | |||||||
| | | | | |||||||
| |
Age: 56
Key Executive Since: June 2023 |
| | |
Experience:
|
| | |||
|
2022-Present:
|
| | BeiGene, Ltd. (Senior Vice President, General Counsel and Assistant Secretary) | | | |||||
|
2016-2022:
|
| | Sanofi SA (General Counsel North America, Head of Legal for General Medicines Global Business) | | | |||||
|
Prior:
|
| | Pfizer Inc. (Chief Counsel Innovative Health Global Business, Chief Counsel Vaccines, Oncology and Consumer Health Global Business and Assistant General Counsel for Asia) | | | |||||
|
Qualifications:
Mr. Lee earned his B.S. in Applied Economics from Cornell University and a J.D. from the University of California at Berkeley. |
| | ||||||||
| | | | |
|
Certain Relationships and Related-Party Transactions
|
|
| Certain Relationships and Related-Party Transactions | |
| Certain Relationships and Related-Party Transactions | |
| Certain Relationships and Related-Party Transactions | |
| Certain Relationships and Related-Party Transactions | |
|
Compensation Committee Interlocks and Insider
Participation |
|
|
Corporate Governance
|
|
| Corporate Governance | |
| Corporate Governance | |
| Corporate Governance | |
| Corporate Governance | |
| Corporate Governance | |
| Corporate Governance | |
| Corporate Governance | |
|
Executive Compensation
|
|
| Executive Compensation | |
Compensation Element
|
| |
Purpose
|
| |
Features
|
|
Base salary
|
| | To attract and retain highly skilled executives | | | Fixed component of pay to provide financial stability, based on responsibilities, experience, individual contributions and peer company data | |
Annual cash incentive program
|
| | To promote and reward the achievement of key short-term strategic and business goals of the Company as well as individual performance; to motivate and attract executives | | | Variable component of pay based on annual corporate and individual performance | |
Equity incentive compensation
|
| | To encourage executives and other employees to focus on long-term Company performance and align their interests with shareholders; to promote retention; to reward outstanding Company and individual performance | | | Typically, subject to multi-year vesting based on continued service and are primarily in the form of share options and RSUs, the value of which depends on the performance of our ADSs, to align employee interests with those of our shareholders over the longer-term | |
| Executive Compensation | |
What We Do
|
| |
What We Don’t Do
|
|
✓
Maintain an industry-specific peer group for benchmarking pay
|
| |
×
No hedging or pledging of equity unless approved by the insider trading compliance officer or the Audit Committee
|
|
✓
Target pay based on market norms
|
| |
×
No re-pricing share options without shareholder approval
|
|
✓
Deliver executive compensation primarily through performance-based pay
|
| |
×
No guaranteed cash or equity compensation increases
|
|
✓
Tie the majority of executive compensation to equity awards, the ultimate value of which is driven by our share price performance
|
| |
×
No supplemental executive retirement plans
|
|
✓
Set challenging short-term incentive award goals
|
| |
×
No excise tax gross-up payments for change-of-control payments
|
|
✓
Offer market-competitive benefits for executives that are consistent with the rest of our employees
|
| | | |
✓
Consult with an independent compensation advisor on compensation levels and practices
|
| | | |
✓
Maintain stock ownership policy for our executive officers equal to 6x base salary for our CEO, 3x base salary for our President and 1x base salary for our other executive officers
|
| | | |
✓
Maintain a broad compensation recovery (“clawback”) policy
|
| | | |
| Executive Compensation | |
Peer Group Criteria
|
| |
General Characteristics
|
|
Industry | | | Biotechnology and pharmaceuticals | |
Relevance | | |
Competitors for labor
Competitors for capital
Comparable scope and complexity
Comparable in terms of R&D/commercialization
|
|
Size | | |
Market capitalization between 0.33x and 3x of BeiGene’s size
Revenue is a secondary consideration because it can lag development
|
|
| Alnylam Pharmaceuticals, Inc. | | | Jazz Pharmaceuticals plc | | | Seagen Inc. | |
| Biogen Inc. | | | Moderna, Inc. | | | United Therapeutics Corporation | |
| BioMarin Pharmaceutical, Inc. | | | Neurocrine Biosciences, Inc. | | | Vertex Pharmaceuticals Inc. | |
| Horizon Therapeutics plc | | | Regeneron Pharmaceuticals, Inc. | | | | |
| Incyte Corporation | | | Sarepta Therapeutics, Inc. | | | | |
| Executive Compensation | |
| Executive Compensation | |
| Executive Compensation | |
| | |
Base Salary
|
| |||||||||||||||
Name
|
| |
2022 (US$)
|
| |
2023 (US$)
|
| |
Increase (%)
|
| |||||||||
John V. Oyler | | | | | 800,000 | | | | | | 871,000 | | | | | | 8.9% | | |
Dr. Xiaobin Wu | | | | | 685,317(1) | | | | | | 756,435(1) | | | | | | 10.4% | | |
Julia Wang | | | | | 560,000 | | | | | | 600,000 | | | | | | 7.1% | | |
Dr. Lai Wang | | | | | 518,497(1) | | | | | | 585,558(1) | | | | | | 12.9% | | |
Chan Lee | | | | | 550,000 | | | | | | 600,000 | | | | | | 9.1% | | |
| Executive Compensation | |
2023 Corporate Goals
|
| |
2023 Corporate Key Achievements
|
| |
Target
Weighting (% Corporate Portion) |
| |
Maximum
Weighting (% Corporate Portion) |
| |
Actual
Achievement for 2023 (as a % of target) |
| |||||||||
Research Innovation
|
| |
Research Innovation Focus
|
| | | | 15% | | | | | | 23% | | | | | | 15% | | |
| | |
Created patient value through scientific discovery and clinical differentiation, with key achievements including:
1.
Selected 10 clinical candidates, all potential first-in-class or best-in-class;
2.
Achieved first patient dosed for 5 assets in first-in-human studies, all potential first-in-class or best-in-class; and
3.
Improved upon several existing internal discovery platforms and expanded in-house research tools and capabilities.
|
| | | | | | | | | | | | | | | | (100)% | | |
Clinical Development
|
| |
World Leading Clinical Development
|
| | | | 15% | | | | | | 23% | | | | | | 16.5% | | |
| | |
Continued to strive towards world leading clinical development, with key achievements including:
1.
Completed key submissions for BRUKINSA in R/R FL;
2.
Submitted two new applications to China NMPA for expanded indication approvals of tislelizumab;
3.
Completed key submissions for TEVIMBRA outside of China including 1L ESCC in the US;
4.
Furthered fast-to-market strategy and expanded indications of BCL2;
5.
Publication in Nature Medicine for TEVIMBRA + BRUKINSA combo in Richter Transformation; and
6.
Improved process for decision making and prioritization in clinical development.
|
| | | | | | | | | | | | | | | | (110)% | | |
| Executive Compensation | |
2023 Corporate Goals
|
| |
2023 Corporate Key Achievements
|
| |
Target
Weighting (% Corporate Portion) |
| |
Maximum
Weighting (% Corporate Portion) |
| |
Actual
Achievement for 2023 (as a % of target) |
| |||||||||
China Leadership
|
| |
China Commercial Leadership
|
| | | | 20% | | | | | | 30% | | | | | | 27% | | |
| | |
Strive to be a commercial leader in China, with key achievements including:
1.
Achieved annual total product sales of US$1.093 million;
2.
Further expanded leading class positions in China for both tislelizumab and BRUKINSA; and
3.
Obtained six new indication approvals in China for tislelizumab and BRUKINSA.
|
| | | | | | | | | | | | | | | | (135)% | | |
Global Leadership
|
| |
Global Leadership, Access & Reputation
|
| | | | 40% | | | | | | 60% | | | | | | 60% | | |
| | |
Build a global reputation as an innovative oncology leader, with key achievements including:
1.
Achieved annual total product sales of US$1,068 million for BRUKINSA in US and Europe, representing 164% annual growth;
2.
Obtained BRUKINSA R/R CLL label update in US and EU based on superior Progression-Free Survival (PFS) over IMBRUVICA® (ibrutinib) in CLL (ALPINE PFS);
3.
Demonstrated durable PFS benefit relative to Imbruvica with extended follow-up (median 39 mo.) of ALPINE study presented at ASH;
4.
Negotiated global rights to TEVIMBRA back from Novartis; and
5.
Obtained approval for TEVIMBRA in Europe as the first approval outside of China.
|
| | | | | | | | | | | | | | | | (150)% | | |
Broader Accessibility
|
| |
Broader Accessibility
|
| | | | 5% | | | | | | 7.5% | | | | | | 4% | | |
| | |
Build a strategic presence in designated New Market regions, with key achievements including:
1.
Expanded approvals for BRUKINSA to a total of 65+ markets;
2.
Obtained CLL approvals for BRUKINSA in key markets including Australia and S. Korea;
3.
Achieved key reimbursement listings for BRUKINSA including for CLL in Australia and for WM in S. Korea; and
4.
Obtained approval for TEVIMBRA in S. Korea as the first approval outside of China and Europe.
|
| | | | | | | | | | | | | | | | (79)% | | |
| Executive Compensation | |
2023 Corporate Goals
|
| |
2023 Corporate Key Achievements
|
| |
Target
Weighting (% Corporate Portion) |
| |
Maximum
Weighting (% Corporate Portion) |
| |
Actual
Achievement for 2023 (as a % of target) |
| |||||||||
Business Maturity
|
| |
Business Maturity
|
| | | | 5% | | | | | | 7.5% | | | | | | 7.5% | | |
| | |
Working to build a more mature global business, with key achievements including:
1.
Recruited and retained key talent, while minimizing unwanted attrition and maintaining employee engagement;
2.
Identified opportunities to build financial and process efficiencies and enable lean business operations and significantly reduce non-GAAP operating loss; and
3.
Achieved 100% successful Health Authority Inspections and timely and successful completion of quality training for key personnel.
|
| | | | | | | | | | | | | | | | (150)% | | |
TOTAL
|
| | | | | | | 100% | | | | | | 150% | | | | | | 130% | | |
| | | | | | | | | | | | | | | | | | | | (130)% | | |
| Executive Compensation | |
Name
|
| |
2023 Target
Award (% of Base Salary) |
| |
2023 Target
Award Opportunity (US$) |
| |
2023 Actual
Bonus Payment (US$) |
| |
2023 Actual Bonus
Payment (% of Target Award Opportunity) |
| ||||||||||||
John V. Oyler | | | | | 100% | | | | | | 871,000 | | | | | | 1,132,300 | | | | | | 130% | | |
Dr. Xiaobin Wu | | | | | 75% | | | | | | 567,259(1) | | | | | | 737,437(1) | | | | | | 130% | | |
Julia Wang | | | | | 60%(2) | | | | | | 360,000 | | | | | | 450,000 | | | | | | 125% | | |
Dr. Lai Wang | | | | | 60%(2) | | | | | | 351,335(1) | | | | | | 456,735(1) | | | | | | 130% | | |
Chan Lee | | | | | 50% | | | | | | 300,000 | | | | | | 390,000 | | | | | | 130% | | |
| Executive Compensation | |
| | |
Option Award
|
| |
RSU Award
|
| ||||||||||||||||||||||||||||||
Name
|
| |
Option
Award (# Ordinary Shares) |
| |
Grant
Date Fair Value (US$) |
| |
Exercise Price
per ordinary shares (US$) |
| |
RSU Award
(# Ordinary Shares) |
| |
Grant
Date Fair Value (US$) |
| |
Total
Grant Date Fair Value (US$) |
| ||||||||||||||||||
John V. Oyler | | | | | 1,349,907 | | | | | | 10,999,987 | | | | | | 16.41 | | | | | | 355,641 | | | | | | 5,499,851 | | | | | | 16,499,838 | | |
Dr. Xiaobin Wu | | | | | 760,851 | | | | | | 6,199,947 | | | | | | 16.41 | | | | | | 200,447 | | | | | | 3,099,836 | | | | | | 9,299,783 | | |
Julia Wang | | | | | 409,058 | | | | | | 3,333,291 | | | | | | 16.41 | | | | | | 107,770 | | | | | | 1,666,622 | | | | | | 4,999,913 | | |
Dr. Lai Wang | | | | | 507,234 | | | | | | 4,133,298 | | | | | | 16.41 | | | | | | 133,627 | | | | | | 2,066,490 | | | | | | 6,199,788 | | |
Chan Lee | | | | | 248,950 | | | | | | 2,028,619 | | | | | | 16.41 | | | | | | 65,585 | | | | | | 1,014,247 | | | | | | 3,042,866 | | |
| Executive Compensation | |
| Executive Compensation | |
| | |
Base Salary
|
| |||||||||||||||
Name
|
| |
2023 (US$)
|
| |
2024 (US$)
|
| |
Increase (%)
|
| |||||||||
John V. Oyler | | | | | 871,000 | | | | | | 1,100,000 | | | | | | 26.3% | | |
Dr. Xiaobin Wu | | | | | 756,345(1) | | | | | | 804,751(1) | | | | | | 6.4% | | |
Julia Wang | | | | | 600,000 | | | | | | 620,000 | | | | | | 3.3% | | |
Dr. Lai Wang | | | | | 585,558(1) | | | | | | 621,862(1) | | | | | | 6.2% | | |
Chan Lee | | | | | 600,000 | | | | | | 621,000 | | | | | | 3.5% | | |
| Executive Compensation | |
| Executive Compensation | |
| Executive Compensation | |
Name and Principal Position |
| |
Year
|
| |
Salary
(US$) |
| |
Share Awards
(US$)(1) |
| |
Option
Awards (US$)(1) |
| |
Non-Equity
Incentive Plan Compensation (US$) |
| |
All Other
Compensation (US$) |
| |
Total
|
| |||||||||||||||||||||
John V. Oyler,
Co-Founder, Chairman and Chief Executive Officer |
| | | | 2023 | | | | | | 871,000 | | | | | | 5,499,851 | | | | | | 10,999,987 | | | | | | 1,132,300(2) | | | | | | 422,592(10) | | | | | | 18,925,730 | | |
| | | 2022 | | | | | | 800,000 | | | | | | 3,999,886 | | | | | | 11,999,969 | | | | | | 1,120,000(6) | | | | | | 127,812 | | | | | | 18,047,667 | | | ||
| | | 2021 | | | | | | 740,000 | | | | | | 3,749,738 | | | | | | 11,249,988 | | | | | | 919,080(7) | | | | | | 89,740 | | | | | | 16,748,546 | | | ||
Dr. Xiaobin Wu,
President, Chief Operating Officer and General Manager of China |
| | | | 2023 | | | | | | 756,345(3) | | | | | | 3,099,836 | | | | | | 6,199,947 | | | | | | 737,437(2)(3) | | | | | | 206,604(11) | | | | | | 11,000,169 | | |
| | | 2022 | | | | | | 721,642(4) | | | | | | 2,249,887 | | | | | | 6,749,952 | | | | | | 757,724(4)(6) | | | | | | 212,688 | | | | | | 10,691,893 | | | ||
| | | 2021 | | | | | | 701,637(5) | | | | | | 1,999,860 | | | | | | 5,999,929 | | | | | | 726,194(5)(7) | | | | | | 211,600 | | | | | | 9,639,220 | | | ||
Julia Wang,
Chief Financial Officer |
| | | | 2023 | | | | | | 600,000 | | | | | | 1,666,622 | | | | | | 3,333,291 | | | | | | 450,000(2) | | | | | | 16,500(8) | | | | | | 6,066,413 | | |
| | | 2022 | | | | | | 560,000 | | | | | | 2,249,925 | | | | | | 3,749,918 | | | | | | 392,000(6) | | | | | | 12,200 | | | | | | 6,964,043 | | | ||
| | | 2021 | | | | | | 445,000 | | | | | | 735,282 | | | | | | 2,206,231 | | | | | | 341,538(7) | | | | | | 11,600 | | | | | | 3,739,651 | | | ||
Dr. Lai Wang,
Global Head of Research and Development |
| | | | 2023 | | | | | | 585,558(3) | | | | | | 2,066,490 | | | | | | 4,133,298 | | | | | | 456,735(2)(3) | | | | | | 74,485(12) | | | | | | 7,316,566 | | |
| | | 2022 | | | | | | 545,979(4) | | | | | | 1,499,977 | | | | | | 4,499,968 | | | | | | 382,185(4)(6) | | | | | | 68,757 | | | | | | 6,996,866 | | | ||
| | | 2021 | | | | | | 526,228(5) | | | | | | 1,374,904 | | | | | | 4,124,931 | | | | | | 363,097(5)(7) | | | | | | 65,711 | | | | | | 6,454,871 | | | ||
Chan Lee, Senior Vice President, General Counsel and Assistant Secretary |
| | | | 2023 | | | | | | 600,000 | | | | | | 1,014,247 | | | | | | 2,028,619 | | | | | | 390,000(2) | | | | | | 16,500(9) | | | | | | 4,049,366 | | |
| Executive Compensation | |
| Executive Compensation | |
Name
|
| | | | | | | |
Estimated Future
Payouts under Non-Equity Incentive Plan Awards(1) |
| |
All Other
Share Awards: Number of Shares or Units (#Ordinary Shares)(2) |
| |
All Other
Option Awards: Number of Securities Underlying Options (#Ordinary Shares)(3) |
| |
Exercise or
Base Price of Shares and Option Awards (US$/Share)(4) |
| |
Grant Date
Fair Value of Share and Option Awards (US$)(5) |
| |||||||||||||||||||||
|
Grant
Date |
| |
Target
(US$) |
| |
Maximum
(US$) |
| |||||||||||||||||||||||||||||||||||
John V. Oyler
|
| | | | | | | | | | 871,000 | | | | | | 1,415,375 | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | 355,641 | | | | | | | | | | | | | | | | | | 5,499,851 | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | 1,349,907 | | | | | | 16.41 | | | | | | 10,999,987 | | | ||
Dr. Xiaobin Wu
|
| | | | | | | | | | 567,259(6) | | | | | | 921,796(6) | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | 200,447 | | | | | | | | | | | | | | | | | | 3,099,836 | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | 760,851 | | | | | | 16.41 | | | | | | 6,199,947 | | | ||
Julia Wang
|
| | | | | | | | | | 360,000 | | | | | | 585,000 | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | 107,770 | | | | | | | | | | | | | | | | | | 1,666,622 | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | 409,058 | | | | | | 16.41 | | | | | | 3,333,291 | | | ||
Dr. Lai Wang
|
| | | | | | | | | | 351,335(6) | | | | | | 570,919(6) | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | 133,627 | | | | | | | | | | | | | | | | | | 2,066,490 | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | 507,234 | | | | | | 16.41 | | | | | | 4,133,298 | | | ||
Chan Lee
|
| | | | | | | | | | 275,000 | | | | | | 446,875 | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | 65,585 | | | | | | | | | | | | | | | | | | 1,014,247 | | | ||
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | | | | | | | 248,950 | | | | | | 16.41 | | | | | | 2,028,619 | | |
| Executive Compensation | |
| | |
Option Awards(1)
|
| |
Stock Awards(2)
|
| ||||||||||||||||||||||||||||||||||||
Name
|
| |
Vesting
Commencement Date |
| |
Number of
Securities Underlying Unexercised Options (#Ordinary Shares) Exercisable |
| |
Number of
Securities Underlying Unexercised Options (#Ordinary Shares) Unexercisable |
| |
Option
Exercise Price (US$) |
| |
Option
Expiration Date |
| |
Number of
Shares That Have Not Vested (#Ordinary Shares) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested (US$)(3) |
| |||||||||||||||||||||
John V. Oyler
|
| | | | 7/19/2015 | | | | | | 11,400,500 | | | | | | — | | | | | | 0.50 | | | | | | 7/19/2025 | | | | | | | | | | | | | | |
| | | 7/13/2016 | | | | | | 2,047,500 | | | | | | — | | | | | | 2.84 | | | | | | 11/15/2026 | | | | | | | | | | | | | | | ||
| | | 6/30/2017 | | | | | | 934,999 | | | | | | — | | | | | | 7.70 | | | | | | 9/26/2027 | | | | | | | | | | | | | | | ||
| | | 4/30/2018 | | | | | | 996,801 | | | | | | — | | | | | | 13.04 | | | | | | 4/29/2028 | | | | | | | | | | | | | | | ||
| | | 6/26/2018 | | | | | | 1,310,088 | | | | | | — | | | | | | 12.34 | | | | | | 6/25/2028 | | | | | | | | | | | | | | | ||
| | | 6/5/2019 | | | | | | 2,193,282 | | | | | | — | | | | | | 9.23 | | | | | | 6/4/2029 | | | | | | | | | | | | | | | ||
| | | 6/17/2020 | | | | | | 1,593,904 | | | | | | 228,072 | | | | | | 13.42 | | | | | | 6/16/2030 | | | | | | | | | | | | | | | ||
| | | 6/16/2021 | | | | | | 566,722 | | | | | | 340,184 | | | | | | 26.53 | | | | | | 6/15/2031 | | | | | | | | | | | | | | | ||
| | | 6/16/2021 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 73,138 | | | | | | 1,014,705 | | | ||
| | | 6/22/2022 | | | | | | 707,863 | | | | | | 1,179,815 | | | | | | 11.98 | | | | | | 6/21/2032 | | | | | | | | | | | | | | | ||
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 250,510 | | | | | | 3,475,537 | | | ||
| | | 6/15/2023 | | | | | | — | | | | | | 1,349,907 | | | | | | 16.41 | | | | | | 6/14/2033 | | | | | | | | | | | | | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 355,641 | | | | | | 4,934,109 | | | ||
Dr. Xiaobin Wu
|
| | | | 4/30/2018 | | | | | | 766,957 | | | | | | — | | | | | | 13.04 | | | | | | 4/29/2028 | | | | | | | | | | | | | | |
| | | 6/5/2019 | | | | | | 797,550 | | | | | | — | | | | | | 9.23 | | | | | | 6/4/2029 | | | | | | | | | | | | | | | ||
| | | 6/17/2020 | | | | | | 661,882 | | | | | | 94,939 | | | | | | 13.42 | | | | | | 6/16/2030 | | | | | | | | | | | | | | | ||
| | | 6/17/2020 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 33,566 | | | | | | 465,690 | | | ||
| | | 6/16/2021 | | | | | | 302,263 | | | | | | 181,415 | | | | | | 26.53 | | | | | | 6/15/2031 | | | | | | | | | | | | | | | ||
| | | 6/16/2021 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 39,000 | | | | | | 541,080 | | | ||
| | | 6/22/2022 | | | | | | 398,125 | | | | | | 663,689 | | | | | | 11.98 | | | | | | 6/21/2032 | | | | | | | | | | | | | | | ||
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 140,907 | | | | | | 1,954,922 | | | ||
| | | 6/15/2023 | | | | | | — | | | | | | 760,851 | | | | | | 16.41 | | | | | | 6/14/2033 | | | | | | | | | | | | | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 200,447 | | | | | | 2,780,971 | | |
| Executive Compensation | |
| | |
Option Awards(1)
|
| |
Stock Awards(2)
|
| ||||||||||||||||||||||||||||||||||||
Name
|
| |
Vesting
Commencement Date |
| |
Number of
Securities Underlying Unexercised Options (#Ordinary Shares) Exercisable |
| |
Number of
Securities Underlying Unexercised Options (#Ordinary Shares) Unexercisable |
| |
Option
Exercise Price (US$) |
| |
Option
Expiration Date |
| |
Number of
Shares That Have Not Vested (#Ordinary Shares) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested (US$)(3) |
| |||||||||||||||||||||
Julia Wang
|
| | | | 6/30/2020 | | | | | | 91,312 | | | | | | 13,442 | | | | | | 14.66 | | | | | | | | | | | | | | | | | | | | |
| | | 6/30/2020 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 13,819 | | | | | | 191,723 | | | ||
| | | 6/16/2021 | | | | | | 111,150 | | | | | | 66,703 | | | | | | 26.53 | | | | | | | | | | | | | | | | | | | | | ||
| | | 6/16/2021 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 14,352 | | | | | | 199,117 | | | ||
| | | 2/28/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 46,319 | | | | | | 642,623 | | | ||
| | | 6/22/2022 | | | | | | 221,182 | | | | | | 368,706 | | | | | | 11.98 | | | | | | 6/21/2032 | | | | | | | | | | | | | | | ||
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 78,286 | | | | | | 1,086,128 | | | ||
| | | 6/15/2023 | | | | | | — | | | | | | 409,058 | | | | | | 16.41 | | | | | | 6/14/2033 | | | | | | | | | | | | | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 107,770 | | | | | | 1,495,184 | | | ||
Dr. Lai Wang
|
| | | | 6/26/2018 | | | | | | 364,208 | | | | | | — | | | | | | 12.34 | | | | | | 6/25/2028 | | | | | | | | | | | | | | |
| | | 6/5/2019 | | | | | | 558,285 | | | | | | — | | | | | | 9.23 | | | | | | 6/4/2029 | | | | | | | | | | | | | | | ||
| | | 6/17/2020 | | | | | | 459,771 | | | | | | 65,793 | | | | | | 13.42 | | | | | | 6/16/2030 | | | | | | | | | | | | | | | ||
| | | 6/17/2020 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 23,309 | | | | | | 323,385 | | | ||
| | | 6/16/2021 | | | | | | 207,610 | | | | | | 124,917 | | | | | | 26.53 | | | | | | 6/15/2031 | | | | | | | | | | | | | | | ||
| | | 6/16/2021 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 26,819 | | | | | | 372,083 | | | ||
| | | 6/22/2022 | | | | | | 265,421 | | | | | | 442,455 | | | | | | 11.98 | | | | | | 6/21/2032 | | | | | | | | | | | | | | | ||
| | | 6/22/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 93,951 | | | | | | 1,303,462 | | | ||
| | | 6/15/2023 | | | | | | — | | | | | | 507,234 | | | | | | 16.41 | | | | | | 6/14/2033 | | | | | | | | | | | | | | | ||
| | | 6/15/2023 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 133,627 | | | | | | 1,853,920 | | | ||
Chan Lee
|
| | | | 7/29/2022 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | 8/5/2022 | | | | | | 66,859 | | | | | | 122,070 | | | | | | 14.96 | | | | | | 8/4/2032 | | | | | | | | | | | | | | | ||
| | | 6/15/2023 | | | | | | — | | | | | | 248,950 | | | | | | 16.41 | | | | | | 6/14/2033 | | | | | | 65,585 | | | | | | 909,916 | | | ||
| | | 6/15/2023 | | | | | | | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Executive Compensation | |
| | |
Option Awards
|
| |
Share Awards
|
| ||||||||||||||||||
Name
|
| |
Number of
Shares Acquired on Exercise (#Ordinary Shares) |
| |
Value
Realized on Exercise (US$)(1) |
| |
Number of
Shares Acquired on Vesting (#Ordinary Shares) |
| |
Value
Realized on Vesting (US$)(2) |
| ||||||||||||
John V. Oyler | | | | | — | | | | | | — | | | | | | 120,055 | | | | | | 1,757,090 | | |
Xiaobin Wu | | | | | — | | | | | | — | | | | | | 438,373 | | | | | | 7,848,615 | | |
Julia Wang | | | | | — | | | | | | — | | | | | | 62,478 | | | | | | 939,249 | | |
Lai Wang | | | | | — | | | | | | — | | | | | | 86,983 | | | | | | 1,336,772 | | |
Chan Lee | | | | | — | | | | | | — | | | | | | 29,003 | | | | | | 502,265 | | |
| Executive Compensation | |
| Executive Compensation | |
| Executive Compensation | |
Executive Benefits and Payment upon Termination
|
| |
Voluntary Resignation
For Good Reason or Termination by Company without Cause (US$) |
| |
Change
in Control (US$) |
| |
Termination by
Company without Cause or Voluntary Resignation for Good Reason Following Change in Control (US$) |
| |||||||||
Compensation: | | | | | | | | | | | | | | | | | | | |
Base salary | | | | | 1,451,667(1) | | | | | | — | | | | | | 1,742,000(7) | | |
Cash incentive bonus | | | | | 891,000(2) | | | | | | — | | | | | | 891,000(2) | | |
Share options unvested and accelerated | | | | | 1,593,020(3) | | | | | | 2,337,898(5) | | | | | | 2,337,898(5) | | |
RSU awards unvested and accelerated | | | | | 5,798,574(4) | | | | | | 9,424,351(6) | | | | | | 9,424,351(6) | | |
Total
|
| | | | 9,734,261 | | | | | | 11,762,249 | | | | | | 14,395,249 | | |
| Executive Compensation | |
Executive Benefits and Payment upon Termination
|
| |
Voluntary Resignation
For Good Reason or Termination by Company without Cause (US$) |
| |
Termination by
Company without Cause or Voluntary Resignation for Good Reason Following Change in Control (US$) |
| ||||||
Compensation: | | | | | | | | | | | | | |
Base salary | | | | | 1,134,518(1) | | | | | | 1,134,518(1) | | |
Cash incentive bonus | | | | | — | | | | | | — | | |
Share options unvested and accelerated | | | | | — | | | | | | 1,300,013(3) | | |
RSU awards unvested and accelerated | | | | | — | | | | | | 5,742,662(4) | | |
Healthcare benefits | | | | | 16,856(2) | | | | | | 16,856(2) | | |
Total
|
| | | | 1,151,374 | | | | | | 8,194,049 | | |
| Executive Compensation | |
Executive Benefits and Payment upon Termination
|
| |
Voluntary Resignation
For Good Reason or Termination by Company without Cause (US$) |
| |
Termination by
Company without Cause or Voluntary Resignation for Good Reason Following Change in Control (US$) |
| ||||||
Compensation: | | | | | | | | | | | | | |
Base salary | | | | | 600,000(1) | | | | | | 600,000(1) | | |
Cash incentive bonus | | | | | — | | | | | | — | | |
Share options unvested and accelerated | | | | | 0(2) | | | | | | 698,272(4) | | |
RSU awards unvested and accelerated | | | | | 191,723(3) | | | | | | 3,641,775(5) | | |
Healthcare benefits | | | | | 736(6) | | | | | | 736(6) | | |
Total
|
| | | | 792,459 | | | | | | 4,913,783 | | |
| Executive Compensation | |
Executive Benefits and Payment upon Termination
|
| |
Voluntary Resignation
For Good Reason or Termination by Company without Cause (US$) |
| |
Termination by
Company without Cause or Voluntary Resignation for Good Reason Following Change in Control (US$) |
| ||||||
Compensation: | | | | | | | | | | | | | |
Base salary | | | | | 600,000(1) | | | | | | 600,000(1) | | |
Cash incentive bonus | | | | | — | | | | | | — | | |
Share options unvested and accelerated | | | | | 0(2) | | | | | | 0(4) | | |
RSU awards unvested and accelerated | | | | | 402,383(3) | | | | | | 2,117,066(5) | | |
Healthcare benefits | | | | | 32,998(6) | | | | | | 32,998(6) | | |
Total
|
| | | | 1,035,381 | | | | | | 2,750,064 | | |
| Executive Compensation | |
| Executive Compensation | |
Year | | | Summary Compensation Table Total for CEO ($)(1) | | | Compensation Actually Paid to CEO ($)(2) | | | Average Summary Compensation Table Total for Non-CEO NEOs ($)(3) | | | Average Compensation Actually Paid to Non-CEO NEOs ($)(2)(3) | | | Value of Initial Fixed $100 Investment Based On: | | | Net Income (Loss) ($) | | | China Net Revenue ($)(5) | | |||||||||||||||||||||||||||
| Total Shareholder Return ($) | | | Peer Group Total Shareholder Return ($)(4) | | ||||||||||||||||||||||||||||||||||||||||||||
2023 | | | | | 18,925,730 | | | | | | 11,431,433 | | | | | | 7,108,129 | | | | | | 6,652,989 | | | | | | 109 | | | | | | 115 | | | | | | (881,708,000) | | | | | | 1,101,951,000 | | |
2022 | | | | | 18,047,667 | | | | | | 11,216,389 | | | | | | 6,355,270 | | | | | | 3,367,166 | | | | | | 133 | | | | | | 111 | | | | | | (2,003,815,000)) | | | | | | 840,032,000 | | |
2021 | | | | | 16,748,546 | | | | | | 22,876,853 | | | | | | 5,143,513 | | | | | | 5,761,306 | | | | | | 163 | | | | | | 125 | | | | | | (1,457,816,000)) | | | | | | 517,104,000 | | |
2020 | | | | | 14,409,330 | | | | | | 40,749,054 | | | | | | 5,178,425 | | | | | | 15,276,116 | | | | | | 156 | | | | | | 126 | | | | | | (1,624,974,000) | | | | | | 290,646,000 | | |
| Executive Compensation | |
| | | 2023($) | | | 2022($) | | | 2021($) | | | 2020($) | | ||||||||||||||||
Summary Compensation Table Values | | | | | 18,925,730 | | | | | | | 18,047,667 | | | | | | | 16,748,546 | | | | | | | 14,409,330 | | | |
Adjustments | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Deduction for grant date fair value amounts reported under “Share Awards” column in the Summary Compensation Table | | | | | (5,499,851 | ) | | | | | | (3,999,886 | ) | | | | | | (3,749,738 | ) | | | | | | — | | | |
Deduction for grant date fair value amounts reported under “Option Awards” column in the Summary Compensation Table | | | | | (10,999,987 | ) | | | | | | (11,999,969 | ) | | | | | | (11,249,988 | ) | | | | | | (12,999,981 | ) | | |
Year-over-Year change in the fair value of the Share Awards and Option Awards | | | | | 9,005,541 | | | | | | | 9,168,577 | | | | | | | 21,128,033 | | | | | | | 39,339,705 | | | |
As of year-end for share awards granted during the year | | | | | 4,934,109 | | | | | | | 5,650,918 | | | | | | | 3,047,963 | | | | | | | — | | | |
Year-over-year increase (decrease) of unvested share awards granted in prior years | | | | | (3,016,530 | ) | | | | | | (5,169,361 | ) | | | | | | (6,167,656 | ) | | | | | | (437,376 | ) | | |
Increase (decrease) from prior fiscal year – end for share awards that vested during the year | | | | | 1,757,090 | | | | | | | 2,790,149 | | | | | | | 8,513,109 | | | | | | | 4,262,798 | | | |
Decrease in fair value of share awards forfeited during the year | | | | | — | | | | | | | — | | | | | | | — | | | | | | | — | | | |
As of year-end for option awards granted during the year | | | | | 8,881,173 | | | | | | | 19,018,564 | | | | | | | 8,085,256 | | | | | | | 21,214,314 | | | |
Year-over-year increase (decrease) of unvested option awards granted in prior years | | | | | (15,862,437 | ) | | | | | | (22,568,170 | ) | | | | | | (22,321,474 | ) | | | | | | (18,976,117 | ) | | |
Increase (decrease) from prior fiscal year – end for option awards that vested during the year | | | | | 12,312,136 | | | | | | | 9,446,478 | | | | | | | 29,970,835 | | | | | | | 33,276,085 | | | |
Decrease in fair value of option awards forfeited during the year | | | | | — | | | | | | | — | | | | | | | — | | | | | | | — | | | |
“Compensation Actually Paid” as defined by SEC rules | | | | | 11,431,433 | | | | | | | 11,216,389 | | | | | | | 22,876,853 | | | | | | | 40,749,054 | | | |
| Executive Compensation | |
| | | 2023($) | | | 2022($) | | | 2021($) | | | 2020($) | | ||||||||||||||||
Average Summary Compensation Table Values | | | | | 7,108,129 | | | | | | | 6,355,270 | | | | | | | 5,143,513 | | | | | | | 5,178,425 | | | |
Adjustments | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Deduction for average grant date fair value of amounts reported to Non-CEO NEOs under “Share Awards” column in the Summary Compensation Table | | | | | (1,961,799 | ) | | | | | | (1,530,694 | ) | | | | | | (1,301,952 | ) | | | | | | (1,066,581 | ) | | |
Deduction for average grant date fair value of amounts reported to Non-CEO NEOs under “Option Awards” column in the Summary Compensation Table | | | | | (3,923,789 | ) | | | | | | (3,878,829 | ) | | | | | | (2,962,605 | ) | | | | | | (3,199,969 | ) | | |
Year-over-Year change in the average fair value of the Share Awards and Option Awards | | | | | 5,430,448 | | | | | | | 2,421,419 | | | | | | | 4,882,350 | | | | | | | 14,364,241 | | | |
As of year-end for share awards granted during the year | | | | | 1,759,998 | | | | | | | 2,027,077 | | | | | | | 773,830 | | | | | | | 1,579,969 | | | |
Year-over-year increase (decrease) of unvested share awards granted in prior years | | | | | (1,396,018 | ) | | | | | | (3,171,371 | ) | | | | | | (1,711,290 | ) | | | | | | 1,084,830 | | | |
Increase (decrease) from prior fiscal year – end for share awards that vested during the year | | | | | 2,656,725 | | | | | | | 1,518,326 | | | | | | | 3,166,184 | | | | | | | 1,653,429 | | | |
Decrease in fair value of share awards forfeited during the year | | | | | — | | | | | | | (307,302 | ) | | | | | | (369,601 | ) | | | | | | — | | | |
As of year-end for option awards granted during the year | | | | | 3,167,990 | | | | | | | 5,943,252 | | | | | | | 2,052,737 | | | | | | | 5,221,946 | | | |
Year-over-year increase (decrease) of unvested option awards granted in prior years | | | | | (3,948,214 | ) | | | | | | (4,561,808 | ) | | | | | | (4,842,349 | ) | | | | | | (2,274,007 | ) | | |
Increase (decrease) from prior fiscal year – end for option awards that vested during the year | | | | | 3,189,968 | | | | | | | 1,981,811 | | | | | | | 7,018,416 | | | | | | | 7,098,075 | | | |
Decrease in fair value of option awards forfeited during the year | | | | | — | | | | | | | (1,008,565 | ) | | | | | | (1,205,576 | ) | | | | | | — | | | |
Average “Compensation Actually Paid” as defined by SEC rules | | | | | 6,652,989 | | | | | | | 3,367,166 | | | | | | | 5,761,306 | | | | | | | 15,276,116 | | | |
| Executive Compensation | |
| Financial Performance Measures | |
| China Net Revenue | |
| North America and Europe BRUKINSA Revenue | |
| Non-GAAP Operating Income (Loss) | |
|
Director Compensation
|
|
| | |
Annual
Retainer (US$) |
| |||
Board of Directors: | | | | | | | |
All independent directors | | | | | 65,000 | | |
Audit Committee: | | | | | | | |
Chairperson (inclusive of fee as a committee member) | | | | | 35,000 | | |
Non-Chairperson members | | | | | 17,500 | | |
Compensation Committee: | | | | | | | |
Chairperson (inclusive of fee as a committee member) | | | | | 30,000 | | |
Non-Chairperson members | | | | | 15,000 | | |
Nominating and Corporate Governance Committee: | | | | | | | |
Chairperson (inclusive of fee as a committee member) | | | | | 20,000(1) | | |
Non-Chairperson members | | | | | 10,000(2) | | |
Commercial and Medical Affairs Advisory Committee: | | | | | | | |
Chairperson (inclusive of fee as a committee member) | | | | | 20,000 | | |
Non-Chairperson members | | | | | 10,000 | | |
Scientific Advisory Committee: | | | | | | | |
Chairperson (inclusive of fee as a committee member) | | | | | 20,000 | | |
Non-Chairperson members | | | | | 10,000 | | |
| Director Compensation | |
| Director Compensation | |
Name(1)
|
| |
Fees Earned or
Paid in Cash (US$) |
| |
Stock
Awards (US$)(2) |
| |
Option
Awards (US$)(2) |
| |
All Other
Compensation (US$) |
| |
Total
(US$) |
| |||||||||||||||
Dr. Margaret Dugan | | | | | 110,750 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 510,547 | | |
Donald W. Glazer | | | | | 81,000 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 480,797 | | |
Michael Goller | | | | | 82,125 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 481,922 | | |
Anthony C. Hooper | | | | | 113,356 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 513,153 | | |
Ranjeev Krishana | | | | | 87,250 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 487,047 | | |
Thomas Malley | | | | | 100,769 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 500,566 | | |
Dr. Alessandro Riva | | | | | 91,875 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 491,672 | | |
Dr. Corsee Sanders | | | | | 101,750 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 501,547 | | |
Dr. Xiaodong Wang(3) | | | | | — | | | | | | — | | | | | | — | | | | | | 7,083,542 | | | | | | 7,083,542 | | |
Qingqing Yi | | | | | 87,250 | | | | | | 199,834 | | | | | | 199,963 | | | | | | — | | | | | | 487,047 | | |
|
Hong Kong Regulatory Information
|
|
Name of Director
|
| |
Nature of interest
|
| |
Number of
ordinary shares |
| |
Approximate
percentage of holding(1) |
| ||||||
John V. Oyler
|
| |
Beneficial owner
|
| | | | 26,171,203(2) | | | | | | 1.93% | | |
| Settlor of a trust / Beneficiary of a trust | | | | | 9,545,000(3) | | | | | | 0.70% | | | ||
|
Settlor of a trust / Interest of a minor child
|
| | | | 102,188(4) | | | | | | 0.01% | | | ||
| Settlor of a trust / Beneficiary of a trust | | | | | 7,727,927(5) | | | | | | 0.57% | | | ||
| Settlor of a trust / Beneficiary of a trust | | | | | 28,984,115(6) | | | | | | 2.13% | | | ||
| Settlor of a trust | | | | | 510,941(7) | | | | | | 0.04% | | | ||
| Interest of a minor child | | | | | 481,533(8) | | | | | | 0.04% | | | ||
| Other | | | | | 1,356,121(9) | | | | | | 0.10% | | | ||
Dr. Xiaodong Wang
|
| |
Beneficial owner
|
| | | | 15,127,403(10) | | | | | | 1.11% | | |
| Interest in controlled corporation | | | | | 4,058,998(11) | | | | | | 0.30% | | | ||
| Other | | | | | 1,127,542(12) | | | | | | 0.08% | | | ||
| Interest of spouse | | | | | 50(13) | | | | | | 0.000004% | | | ||
Dr. Olivier Brandicourt | | | Beneficial owner | | | | | 27,794(14) | | | | | | 0.002% | | |
Dr. Margaret Dugan | | | Beneficial owner | | | | | 113,815(15) | | | | | | 0.0058% | | |
Donald W. Glazer | | | Beneficial owner | | | | | 3,108,659(16) | | | | | | 0.23% | | |
Michael Goller | | |
Person having a security interest in shares
|
| | | | 453,232(17) | | | | | | 0.03% | | |
Anthony C. Hooper | | | Beneficial owner | | | | | 183,885(18) | | | | | | 0.01% | | |
Ranjeev Krishana | | |
Person having a security interest in shares
|
| | | | 453,232(19) | | | | | | 0.03% | | |
Dr. Alessandro Riva | | | Beneficial owner | | | | | 113,815(20) | | | | | | 0.008% | | |
Dr. Corazon (Corsee) D. Sanders | | | Beneficial owner | | | | | 136,500(21) | | | | | | 0.01% | | |
Qingqing Yi | | | Beneficial owner | | | | | 436,150(22) | | | | | | 0.03% | | |
| Hong Kong Regulatory Information | |
| Hong Kong Regulatory Information | |
Name of Shareholder
|
| |
Capacity / Nature of interest
|
| |
Number
of ordinary shares / underlying shares |
| |
Approximate
percentage of holding(1) |
| ||||||
Amgen Inc. | | | Beneficial owner | | | | | 246,269,426 | | | | | | 18.11% | | |
Julian C. Baker(2) | | | Beneficial owner / Interest in controlled corporations / Person having a security interest in shares |
| | | | 138,757,831 | | | | | | 10.21% | | |
Felix J. Baker(2) | | | Beneficial owner / Interest in controlled corporations / Person having a security interest in shares |
| | | | 138,757,831 | | | | | | 10.21% | | |
Baker Bros. Advisors (GP) LLC(2) | | | Investment manager / Other | | | | | 138,302,171 | | | | | | 10.17% | | |
Baker Bros. Advisors LP(2) | | | Investment manager / Other | | | | | 138,302,171 | | | | | | 10.17% | | |
Baker Brothers Life Sciences Capital, L.P.(2)
|
| | Interest in controlled corporations / Other | | | | | 126,893,311 | | | | | | 9.33% | | |
HHLR Advisors, Ltd.(3) | | | Investment manager | | | | | 133,587,655 | | | | | | 9.83% | | |
HHLR Fund, L.P.(3) | | | Beneficial owner | | | | | 129,433,059 | | | | | | 9.52% | | |
The Capital Group Companies, Inc.(4) | | | Interest in controlled corporations | | | | | 110,035,453 | | | | | | 8.09% | | |
JPMorgan Chase & Co.(5) | | | Interest in controlled corporations | | | | | 11,616,854 | | | | | | 0.85% | | |
| | | | | | | | 11,041,136(S) | | | | | | 0.81% | | |
| | | Investment manager | | | | | 362,539 | | | | | | 0.03% | | |
| | | Person having a security interest in shares | | | | | 107,612 | | | | | | 0.01% | | |
| | | Trustee | | | | | 5,954 | | | | | | 0.0004% | | |
| | | Approved lending agent | | | | | 97,364,256 | | | | | | 7.16% | | |
| Hong Kong Regulatory Information | |
| Hong Kong Regulatory Information | |
Name
|
| |
Qualification
|
|
Anglo Chinese Corporate Finance, Limited | | | A corporation licensed to conduct Type 1 (dealing in securities), Type 4 (advising on securities), Type 6 (advising on corporate finance) and Type 9 (asset management) regulated activities under the SFO | |
| Hong Kong Regulatory Information | |
|
Forward-looking Statements
|
|
|
Delivery of Proxy Materials
|
|
|
EACH SHAREHOLDER IS URGED TO COMPLETE, DATE, SIGN AND
PROMPTLY RETURN THE ENCLOSED FORM OF PROXY. |
|
|
Appendix A
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| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
| Appendix A | |
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Appendix B
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|
| Appendix B | |
| Appendix B | |
| Appendix B | |
| Appendix B | |
| Appendix B | |
| Appendix B | |
|
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| | |
|
FORM OF PROXY
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I/We
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Please Print Name(s)
|
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of
|
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Please Print Address(es)
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of
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Please Print Name
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Please Print Address
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For
|
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Against
|
| |
Abstain
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|
Resolution 1 — Ordinary Resolution
THAT Dr. Olivier Brandicourt be and is hereby re-elected to serve as a Class II director of the Company until the 2027 annual general meeting of the shareholders of the Company and until his successor is duly elected and qualified, subject to his earlier resignation or removal. |
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☐
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☐
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☐
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Resolution 2 — Ordinary Resolution
THAT Donald W. Glazer be and is hereby re-elected to serve as a Class II director of the Company until the 2027 annual general meeting of the shareholders of the Company and until his successor is duly elected and qualified, subject to his earlier resignation or removal. |
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☐
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☐
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☐
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Resolution 3 — Ordinary Resolution
THAT Michael Goller be and is hereby re-elected to serve as a Class II director until the 2027 annual general meeting of shareholders and until his successor is duly elected and qualified, subject to his earlier resignation or removal. |
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☐
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☐
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☐
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Resolution 4 — Ordinary Resolution
THAT Dr. Corazon (Corsee) D. Sanders be and is hereby re-elected to serve as a Class II director until the 2027 annual general meeting of shareholders and until her successor is duly elected and qualified, subject to her earlier resignation or removal. |
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☐
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☐
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☐
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Resolution 5 — Ordinary Resolution
THAT the appointment of Ernst & Young LLP, Ernst & Young and Ernst & Young Hua Ming LLP as the Company’s independent auditors for the fiscal year ending December 31, 2024 be and is hereby approved, ratified and confirmed. |
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☐
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☐
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☐
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Resolution 6 — Ordinary Resolution
THAT the Board of Directors is hereby authorized to fix the auditors’ compensation for the fiscal year ending December 31, 2024. |
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☐
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☐
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☐
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Resolution 7 — Ordinary Resolution
THAT the granting of a share issue mandate to the Board of Directors to issue, allot or deal with unissued ordinary shares and/or American Depositary Shares (“ADSs”) not exceeding 20% of the total number of issued shares of the Company as of the date of passing of this ordinary resolution up to the next annual general meeting of shareholders of the Company be and is hereby approved. |
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☐
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☐
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For
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Against
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Abstain
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Resolution 8 — Ordinary Resolution
THAT the granting of a share repurchase mandate to the Board of Directors to repurchase an amount of ordinary shares (excluding RMB shares) and/or ADSs, not exceeding 10% of the total number of issued ordinary shares (excluding RMB shares) of the Company as of the date of passing of such ordinary resolution up to the next annual general meeting of shareholders of the Company be and is hereby approved. |
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☐
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☐
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☐
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Resolution 9 — Ordinary Resolution
THAT the Company and its underwriters be and are hereby authorized, in their sole discretion, to allocate to each of Baker Bros. Advisors LP and Hillhouse Capital Management, Ltd. and parties affiliated with each of them (the “Existing Shareholders”), up to a maximum amount of shares in order to maintain the same shareholding percentage of each of the Existing Shareholders (based on the then-outstanding share capital of the Company) before and after the allocation of the corresponding securities issued pursuant to an offering conducted pursuant to the general mandate set forth in Resolution 6 for a period of five years, which period will be subject to an extension on a rolling basis each year. |
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☐
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☐
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☐
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Resolution 10 — Ordinary Resolution
THAT the Company and its underwriters be and are hereby authorized, in their sole discretion, to allocate to Amgen Inc. (“Amgen”), up to a maximum amount of shares in order to maintain the same shareholding percentage of Amgen (based on the then-outstanding share capital of the Company) before and after the allocation of the corresponding securities issued pursuant to an offering conducted pursuant to the general mandate set forth in Resolution 6 for a period of five years, which period will be subject to an extension on a rolling basis each year. |
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☐
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☐
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☐
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Resolution 11 — Ordinary Resolution
THAT the grant of restricted share units (“RSUs”) with a grant date fair value of US$6,000,000 to Mr. John V. Oyler under the Second Amended and Restated 2016 Share Option and Incentive Plan (as amended, the “2016 Plan”), according to the terms and conditions described in the Proxy Statement, be and is hereby approved. |
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☐
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☐
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☐
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Resolution 12 — Ordinary Resolution
THAT the grant of performance share units (“PSUs”) with a grant date fair value of US$6,000,000 to Mr. John V. Oyler under the 2016 Plan, according to the terms and conditions described in the Proxy Statement, be and is hereby approved. |
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☐
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☐
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☐
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Resolution 13 — Ordinary Resolution
THAT the grant of RSUs with a grant date fair value of US$1,333,333 to Dr. Xiaodong Wang under the 2016 Plan, according to the terms and conditions described in the Proxy Statement, be and is hereby approved. |
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☐
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☐
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☐
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Resolution 14 — Ordinary Resolution
THAT the grant of RSUs with a grant date fair value of US$200,000 to each of the independent non-executive directors, Dr. Olivier Brandicourt, Dr. Margaret Dugan, Mr. Donald W. Glazer, Mr. Michael Goller, Mr. Anthony C. Hooper, Mr. Ranjeev Krishana, Dr. Alessandro Riva, Dr. Corazon (Corsee) D. Sanders, and Mr. Qingqing Yi, under the 2016 Plan, according to the terms and conditions described in the Proxy Statement, be and is hereby approved. |
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☐
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☐
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☐
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Resolution 15 — Ordinary Resolution
THAT, on a non-binding, advisory basis, the compensation of the Company’s named executive officers, as disclosed in the Proxy Statement, be and is hereby approved. |
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☐
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☐
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☐
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Resolution 16 — Ordinary Resolution
THAT, on a non-binding, advisory basis, the frequency of future advisory votes on the compensation of the Company’s named executive officers will be held at the frequency hereby approved. |
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1 year
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2 years
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3 years
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Resolution 17(a) — Ordinary Resolution
THAT the Third Amended and Restated 2016 Share Option and Incentive Plan of the Company, as described in the Proxy Statement, be and is hereby approved. |
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Resolution 17(b) — Ordinary Resolution
THAT the consultant sublimit set out in the Third Amended and Restated 2016 Share Option and Incentive Plan of the Company, as described in the Proxy Statement, be and is hereby approved. |
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Resolution 18 — Ordinary Resolution
THAT the Fourth Amended and Restated 2018 Employee Share Purchase Plan of the Company, as described in the Proxy Statement, be and is hereby approved. |
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For
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Against
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Abstain
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Resolution 19 — Ordinary Resolution
THAT the adjournment of the Annual Meeting by the chairman, if necessary, to solicit additional proxies if there are insufficient votes at the time of the Annual Meeting to approve any of the proposals described above, be and is hereby approved. |
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| Signed: | | | | | | Date: | | | | | | 2024 | |
| Name: | | | | | | | | | | | | | |
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